Intervention to reduce excessive alcohol consumption and improve comorbidity outcomes in hypertensive or depressed primary care patients: two parallel cluster randomized feasibility trials

Wilson, Graeme, B., Wray, Catherine, Newbury-Birch, Dorothy, McColl, Elaine, Crosland, Ann, Speed, Chris, Cassidy, Paul, Tomson, Dave, Haining, Shona, Howel, Denise and Kaner, Eileen F. S. (2014) Intervention to reduce excessive alcohol consumption and improve comorbidity outcomes in hypertensive or depressed primary care patients: two parallel cluster randomized feasibility trials. Trials, 15 (235). ISSN 1745-6215 (In Press)

[img]
Preview
PDF
Intervention_to_Reduce_Excessive_Alcohol_Consumption.pdf - Published Version

Download (849kB)

Abstract

Wilson, G. B.
Wray, C.
McGovern, R.
Newbury-Birch, D.
McColl, E.
Crosland, A.
Background

Many primary care patients with raised blood pressure or depression drink potentially hazardous levels of alcohol. Brief interventions (BI) to reduce alcohol consumption may
improve comorbid conditions and reduce the risk of future alcohol problems. However,research has not established their effectiveness in this patient population. This study aimed to establish the feasibility of definitive trials of BI to reduce excessive drinking in primary care patients with hypertension or mild to moderate depression.

Methods

Thirteen general practices in North East England were randomized to the intervention or control arm of one of two parallel pilot trials. Adult patients drinking excessively and diagnosed with hypertension or mild-to-moderate depression received the Alcohol Use Disorders Identification Test (AUDIT) by postal survey. Consenting respondents scoring more than 7 on AUDIT (score range 0 to 40) received brief alcohol consumption advice plus
an information leaflet (intervention) or an information leaflet alone(control) with follow-up at six months. Measurements included the numbers of patients eligible, recruited, and retained, and the AUDIT score and systolic/diastolic blood pressure of each patient or the nine-item Patient Health Questionnaire (PHQ-9) score. Acceptability was assessed via practitioner feedback and patient willingness to be screened, recruited, and retained at follow-up.

Results

In the hypertension trial, 1709 of 33,813 adult patients(5.1%) were eligible and were surveyed. Among the eligible patients, 468 (27.4%) returned questionnaires; 166 (9.6% of those surveyed) screened positively on AUDIT and 83 (4.8% of those surveyed) were recruited (50.0% of positive screens). Sixty-seven cases (80.7% of recruited patients)completed follow-up at six months. In the depression trial, 1,044 of 73,146 adult patients(1.4%)were eligible and surveyed. Among these eligible patients, 215(20.6%)responded;104(10.0% of those surveyed)screened positively on AUDIT and 29 (2.8% of those surveyed) were recruited (27.9% of positive screens). Nineteen cases(65.5% of recruited patients)completed follow-up at six months.

Conclusions

Recruitment and retention rates were higher in the hypertension trial than in the depression trial. A full brief intervention trial appears feasible for primary care patients with hypertension who drink excessively. High AUDIT scores in the depression trial suggest the
importance of alcohol intervention in this group. However, future work may require alternative screening and measurement procedures.

Item Type: Article
Uncontrolled Keywords: Alcohol, Screening, Brief intervention, Comorbid, Hypertension, Depression, Primary care, Trial, Preventive, Feasibility
Subjects: Sciences > Health Sciences
Divisions: Faculty of Applied Sciences
Faculty of Applied Sciences > Department of Pharmacy Health and Wellbeing
Health Sciences and Wellbeing Beacon
Depositing User: Hannah Dodd
Date Deposited: 30 Jun 2014 08:06
Last Modified: 09 Mar 2017 09:34
URI: http://sure.sunderland.ac.uk/id/eprint/5002

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year