Enantioselective separation of enantiomeric amides on three amylose-based chiral stationary phases: Effects of backbone and carbamate side chain chiralities Authors

Booth, T.D., Lough, John, Saeed, M., Noctor, T.A.G. and Wainer, I.W. (1997) Enantioselective separation of enantiomeric amides on three amylose-based chiral stationary phases: Effects of backbone and carbamate side chain chiralities Authors. Chirality, 9 (2). pp. 173-177. ISSN 1520-636X

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Abstract

A series of enantiomeric amides have been chromatographed on three amylose-based chiral stationary phases (CSPs): amylose tris(3,5-dimethylphenylcarbamate) (AD-CSP), amylose tris (S-phenylethylcarbamate) (AS-CSP), and amylose tris(R-phenylethyl-carbamate) (AR-CSP). The relative retentions and enantioselectives of the solutes on the three CSPs were compared and basic structure-retention relationships developed to describe the chromatographic results. The data indicate that for these solutes the observed elution order was a function of the chirality of the amylose backbone, while the magnitude of the enantioselective separations was affected by the chirality of the carbamate side chain. Chirality 9:173–177, 1997. © 1997 Wiley-Liss, Inc.

Item Type: Article
Subjects: Sciences
Divisions: Faculty of Applied Sciences
Faculty of Applied Sciences > Department of Pharmacy Health and Wellbeing
Depositing User: Paula Normington
Date Deposited: 09 Jun 2017 10:51
Last Modified: 09 Jun 2017 10:51
URI: http://sure.sunderland.ac.uk/id/eprint/6417

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