The two faces of Rsk2 in hyperplastic disease
Falconer, Jane and Buckley, CD (2015) The two faces of Rsk2 in hyperplastic disease. Nature Reviews Rheumatology. ISSN 1759-4804
| Item Type: | Article |
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Abstract
Given the established role of 90 kDa ribosomal S6 kinases (Rsk) in oncogenesis, and the promise of new Rsk-blocking cancer treatments, it is perhaps surprising that Rsk2-mediated inhibition of hyperplasia has now been demonstrated to occur in the arthritic synovium. Does this functional duality make Rsk2 a risky target for the treatment of rheumatoid arthritis?
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| Depositing User: Jane Falconer |
Identifiers
| Item ID: 11088 |
| Identification Number: https://doi.org/10.1038/nrrheum.2015.1 |
| ISSN: 1759-4804 |
| URI: http://sure.sunderland.ac.uk/id/eprint/11088 | Official URL: https://www.nature.com/articles/nrrheum.2015.1 |
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| Date Deposited: 05 Sep 2019 09:45 |
| Last Modified: 30 Sep 2020 11:30 |
| Author: |
Jane Falconer
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| Author: | CD Buckley |
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