The two faces of Rsk2 in hyperplastic disease

Falconer, Jane and Buckley, CD (2015) The two faces of Rsk2 in hyperplastic disease. Nature Reviews Rheumatology. ISSN 1759-4804

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Abstract

Given the established role of 90 kDa ribosomal S6 kinases (Rsk) in oncogenesis, and the promise of new Rsk-blocking cancer treatments, it is perhaps surprising that Rsk2-mediated inhibition of hyperplasia has now been demonstrated to occur in the arthritic synovium. Does this functional duality make Rsk2 a risky target for the treatment of rheumatoid arthritis?

Item Type: Article
Divisions: Faculty of Health Sciences and Wellbeing > School of Medicine
Depositing User: Jane Falconer
Date Deposited: 05 Sep 2019 09:45
Last Modified: 05 Sep 2019 13:23
URI: http://sure.sunderland.ac.uk/id/eprint/11088
ORCID for Jane Falconer: ORCID iD orcid.org/0000-0002-6601-7919

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