Editorial: Environmental Genomics and Epigenomics: Response, Development and Disease

Li, Yanqiang, Byun, Hyang-Min, Barrow, Timothy and Zhang, Qiang (2021) Editorial: Environmental Genomics and Epigenomics: Response, Development and Disease. Frontiers Media S.A..

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With the rapid process of industrialization and the growth of the human population to unprecedented levels, individuals are increasingly exposed to multiple pollutants known to have an adverse impact upon human health, such as heavy metals, endocrine disruptors, tobacco smoke, polychlorinated biphenyls, diesel exhaust particles, pesticides, and other indoor and outdoor pollutants. Multiple non-communicable diseases (NCDs), including stroke, heart disease, cancers and chronic respiratory disease, now amount to nearly two-thirds of the total deaths caused by unhealthy environments. Considering this global burden, it is vital to understand the mechanisms underpinning the associations between environmental exposures and NCDs. Many studies have demonstrated that the epigenome can be altered by the environmental exposures, but the functional role of these changes in the processes of diseases have not been fully elucidated. This Research Topic has collated high-quality studies in the form of five reviews and four original research papers covering the genetic and epigenetic response to a range of environmental exposures.

Item Type: Other
Additional Information: ** From Frontiers via Jisc Publications Router ** History: collection 2021; received 12-04-2021; accepted 20-04-2021; epub 20-05-2021. ** Licence for this article: http://creativecommons.org/licenses/by/4.0/
Uncontrolled Keywords: Genetics, environmental exposures, DNA methylation, histone modification, epigenetics, disease
Divisions: Faculty of Health Sciences and Wellbeing > School of Nursing and Health Sciences
Related URLs:
SWORD Depositor: Publication Router
Depositing User: Publication Router
Date Deposited: 22 Jun 2021 10:51
Last Modified: 22 Jun 2021 11:00
URI: http://sure.sunderland.ac.uk/id/eprint/13562
ORCID for Timothy Barrow: ORCID iD orcid.org/0000-0003-4551-3857

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