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Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

Development and Characterisation of Polymeric Nanacapsules Containing Macromolecule

Abu Abed, O. S., Elkordy, Amal, Chaw, Cheng, Williams, Lee and Carlile, Mark (2016) Development and Characterisation of Polymeric Nanacapsules Containing Macromolecule. Molecular Therapy, 24 (Supp 1). S237-S238. ISSN 1525-0016

Item Type: Article


Oral drug delivery systems are the most common route of administration. However,
development oral delivery system containing macromolecules is still challenging due to
different hurdles, including, digestive enzymes degradation and physiochemical
properties of the molecules. Currently, several techniques have been applied to deliver
the macromolecules orally e.g. polymer conjugates, excipients such as cyclodextrin, and
entrapment inside carriers, such as liposomes, and nanocapsule systems. Accordingly, the
aim of this study is to overcome these challenges by encapsulating macromolecule inside
polymeric nanocapsules, trypsin as a protein was used as a model macromolecule.

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More Information

Depositing User: Amal Elkordy


Item ID: 6307
Identification Number:
ISSN: 1525-0016
Official URL:

Users with ORCIDS

ORCID for Amal Elkordy: ORCID iD
ORCID for Cheng Chaw: ORCID iD

Catalogue record

Date Deposited: 11 May 2016 08:04
Last Modified: 16 May 2022 13:00


Author: Amal Elkordy ORCID iD
Author: Cheng Chaw ORCID iD
Author: O. S. Abu Abed
Author: Lee Williams
Author: Mark Carlile

University Divisions

Faculty of Health Sciences and Wellbeing
Faculty of Health Sciences and Wellbeing > School of Pharmacy and Pharmaceutical Sciences


Sciences > Pharmacy and Pharmacology

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