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Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

Theoretical Considerations and a Mathematical Model for the Analysis of the Biomechanical Response of Human Keratinized Oral Mucosa

Tsaira, Aikaterini, Karagiannidis, Panagiotis, Sidira, Margarita, Kassavetis, Spyros, Kugiumtzis, Dimitris, Logothetidis, Stergios, Naka, Olga, Pissiotis, Argirios and Michalakis, Konstantinos (2016) Theoretical Considerations and a Mathematical Model for the Analysis of the Biomechanical Response of Human Keratinized Oral Mucosa. Frontiers in Physiology, 7. p. 364. ISSN 1664-042X

Item Type: Article


Removable complete and partial dentures are supported by the residual alveolar ridges consisting of mucosa, submucosa, periosteum, and bone. An understanding of the biomechanical behavior of the oral mucosa is essential in order to improve the denture-bearing foundations for complete and partially edentulous patients. The purpose of this paper was to examine the biomechanical behavior of the soft tissues supporting a removable denture and develop a model for that reason. Keratinized oral mucosa blocks with their underlying bone were harvested from the maxillary palatal area adjacent to the edentulous ridges of a cadaver. The compressive response of the oral mucosa was tested by using atomic force microscopy. The specimens were first scanned in order their topography to be obtained. The mechanical properties of the specimens were tested using a single crystal silicon pyramidal tip, which traversed toward the keratinized oral mucosa specimens. Loading-unloading cycles were registered and four mathematical models were tested using MATLAB to note which one approximates the force-displacement curve as close as possible: a. spherical, b. conical, c. third order polynomial, d. Murphy (fourth order polynomial, non-linear Hertzian based). The third order polynomial model showed the best accuracy in representing the force-displacement data of the tested specimens. A model was developed in order to analyze the biomechanical behavior of the human oral keratinized mucosa and obtain information about its mechanical properties.

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Depositing User: Panagiotis Karagiannidis


Item ID: 7762
Identification Number:
ISSN: 1664-042X
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ORCID for Panagiotis Karagiannidis: ORCID iD

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Date Deposited: 22 Sep 2017 14:02
Last Modified: 04 Feb 2021 11:40


Author: Panagiotis Karagiannidis ORCID iD
Author: Aikaterini Tsaira
Author: Margarita Sidira
Author: Spyros Kassavetis
Author: Dimitris Kugiumtzis
Author: Stergios Logothetidis
Author: Olga Naka
Author: Argirios Pissiotis
Author: Konstantinos Michalakis

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