This paper focuses on the tourism impacts of the 2015-16 refugee crisis in Greece. It examines the implications of the related publicity for the perception of Greece and the expected reaction of inbound tourists; the way refugees are regarded from a security and cultural aspect; the interaction between refugees and host communities; and the decisions made by the Greek tourism accommodation sector to face the crisis. Using fuzzy-set Qualitative Comparative Analysis the paper employs a nationwide survey of 811 tourism accommodation managers. The results reveal three configurations explaining the decisions of respondents characterized by refugee-centric orientation; the emphasis on the visitors-locals nexus; and the host communities’ behavioural impact on tourism. The paper also compares asymmetric with symmetric analysis highlighting the suitability of the former when dealing with complexity. The modelling exercise also steps forward from fit to predictive validity. The findings contribute to both managerial and methodological aspects of tourism.