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Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

Effect of high-vacuum setting on phacoemulsification efficiency

Ting, Darren Shu Jeng, Rees, Jon, Ng, Jia Yu, Allen, David and Steel, David HW (2017) Effect of high-vacuum setting on phacoemulsification efficiency. Journal of Cataract & Refractive Surgery, 43 (9). pp. 1135-1139. ISSN 0886-3350

Item Type: Article


To evaluate the effect of a high-vacuum setting versus a low-vacuum setting on the efficiency of phacoemulsification.

Sunderland Eye Infirmary, Sunderland, United Kingdom.

Prospective clinical trial.

Consecutive patients having cataract surgery in 2014 were recruited. Cataract surgery was performed by 2 experienced surgeons using a phacoemulsification machine with monitored forced infusion. The cataractous lens was split into 2 heminuclei using the stop-and-chop technique; in 1 heminucleus, phacoemulsification and aspiration used a high-vacuum setting (600 mm Hg; treatment group) and in the other heminucleus, a low-vacuum setting (350 mm Hg; control group). The high and low settings were alternated by case per the operating list to reduce surgeon bias. The main outcome measures were cumulative dissipated energy (CDE) and active heminucleus removal time.

One hundred sixty patients (160 eyes) were enrolled in the study, and 158 were included in the analysis. The CDE per heminucleus was significantly lower with the high-vacuum setting than with the low-vacuum setting (mean 2.81 percent-seconds; 95% confidence interval (CI), 2.44-3.21 versus 3.81 percent-seconds; 95% CI, 3.38-4.20; P < .001). The active heminucleus removal time was significantly shorter in the high-vacuum group than the low-vacuum group (mean 27.77 seconds; 95% CI, 25.26-30.19 versus 33.59 seconds; 95% CI, 31.07-35.92; P < .001). The observed differences were independent of the surgeon, patient age and sex, incision size, and nucleus density. No intraoperative complications were observed in either group.

A high-vacuum setting improved phacoemulsification efficiency using an active fluidics system and torsional phacoemulsification

9458 High vacuum paper final version.pdf - Accepted Version
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More Information

Depositing User: Jon Rees


Item ID: 9458
Identification Number:
ISSN: 0886-3350
Official URL:

Users with ORCIDS

ORCID for Jon Rees: ORCID iD

Catalogue record

Date Deposited: 17 May 2018 13:03
Last Modified: 14 May 2020 10:42


Author: Jon Rees ORCID iD
Author: Darren Shu Jeng Ting
Author: Jia Yu Ng
Author: David Allen
Author: David HW Steel

University Divisions

Faculty of Health Sciences and Wellbeing > School of Psychology


Sciences > Biomedical Sciences

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