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The two faces of Rsk2 in hyperplastic disease

Falconer, Jane and Buckley, CD (2015) The two faces of Rsk2 in hyperplastic disease. Nature Reviews Rheumatology. ISSN 1759-4804

Item Type: Article

Abstract

Given the established role of 90 kDa ribosomal S6 kinases (Rsk) in oncogenesis, and the promise of new Rsk-blocking cancer treatments, it is perhaps surprising that Rsk2-mediated inhibition of hyperplasia has now been demonstrated to occur in the arthritic synovium. Does this functional duality make Rsk2 a risky target for the treatment of rheumatoid arthritis?

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More Information

Depositing User: Jane Falconer

Identifiers

Item ID: 11088
Identification Number: https://doi.org/10.1038/nrrheum.2015.1
ISSN: 1759-4804
URI: http://sure.sunderland.ac.uk/id/eprint/11088
Official URL: https://www.nature.com/articles/nrrheum.2015.1

Users with ORCIDS

ORCID for Jane Falconer: ORCID iD orcid.org/0000-0002-6601-7919

Catalogue record

Date Deposited: 05 Sep 2019 09:45
Last Modified: 30 Sep 2020 11:30

Contributors

Author: Jane Falconer ORCID iD
Author: CD Buckley

University Divisions

Faculty of Health Sciences and Wellbeing > School of Medicine

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