Marked for death.
Petrie, Kevin and Zelent, Arthur (2008) Marked for death. Nature cell biology, 10 (5). pp. 507-9. ISSN 1476-4679
| Item Type: | Article |
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Abstract
SUMOylation of PML–RARα oncoprotein has been linked to its arsenic-induced degradation and the therapeutic response in acute promyelocytic leukaemia. Two groups identify PML as an in vivo target of the RING finger ubiquitin E3 ligase RNF4, which specifically binds polySUMOylated PML and is essential for the arsenic-induced catabolism of both PML and PML–RARα.
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2008 Marked for death accepted version.pdf - Accepted Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (747kB) | Preview |
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| Depositing User: Kevin Petrie |
Identifiers
| Item ID: 12430 |
| Identification Number: https://doi.org/10.1038/ncb0508-507 |
| ISSN: 1476-4679 |
| URI: http://sure.sunderland.ac.uk/id/eprint/12430 | Official URL: https://www.nature.com/articles/ncb0508-507 |
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Catalogue record
| Date Deposited: 18 Aug 2020 13:00 |
| Last Modified: 30 Sep 2020 10:48 |
| Author: |
Kevin Petrie
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| Author: | Arthur Zelent |
University Divisions
Faculty of Health Sciences and Wellbeing > School of MedicineSubjects
Sciences > Biomedical SciencesSciences > Health Sciences
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