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The genome of the model beetle and pest Tribolium castaneum

Butts, Thomas and Tribolium Genome Sequencing Consortium, (2008) The genome of the model beetle and pest Tribolium castaneum. Nature, 452 (7190). pp. 949-955. ISSN 0028-0836

Item Type: Article

Abstract

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell–cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.

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More Information

Depositing User: Leah Maughan

Identifiers

Item ID: 14359
Identification Number: https://doi.org/10.1038/nature06784
ISSN: 0028-0836
URI: http://sure.sunderland.ac.uk/id/eprint/14359
Official URL: http://dx.doi.org/10.1038/nature06784

Users with ORCIDS

ORCID for Thomas Butts: ORCID iD orcid.org/0000-0002-1781-5287

Catalogue record

Date Deposited: 17 Jan 2022 15:19
Last Modified: 17 Jan 2022 15:19

Contributors

Author: Thomas Butts ORCID iD
Author: Tribolium Genome Sequencing Consortium

University Divisions

Faculty of Health Sciences and Wellbeing > School of Medicine

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