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Hormonal control of metabolism: regulation of plasma glucose

Yeo, Robert and Sawdon, Marina (2017) Hormonal control of metabolism: regulation of plasma glucose. Anaesthesia & Intensive Care Medicine, Anaesthesia & Intensive Care Medicine, 14 (7). pp. 296-300. ISSN 1472-0299

Item Type: Article

Abstract

The control of plasma glucose needs to be tightly monitored because hyperglycaemia and hypoglycaemia can lead to severe clinical problems, including death. In this article the major mechanism for the transport of glucose into and out of the blood and how that mechanism is used to monitor the circulating concentrations of glucose are discussed. A number of hormones regulate glucose in response to changes in plasma concentrations. Insulin promotes the removal of glucose and its conversion to glycogen. Glucagon, in response to falling glucose concentrations, increases the breakdown of glycogen and the release of glucose from the liver. There are many other hormones that play a part in assisting the functions of insulin and glucagon. Failures in the appropriate production of such hormones may lead to the unregulated changes in plasma glucose and subsequent health problems.The control of plasma glucose needs to be tightly monitored because hyperglycaemia and hypoglycaemia can lead to severe clinical problems, including death. In this article the major mechanism for the transport of glucose into and out of the blood and how that mechanism is used to monitor the circulating concentrations of glucose are discussed. A number of hormones regulate glucose in response to changes in plasma concentrations. Insulin promotes the removal of glucose and its conversion to glycogen. Glucagon, in response to falling glucose concentrations, increases the breakdown of glycogen and the release of glucose from the liver. There are many other hormones that play a part in assisting the functions of insulin and glucagon. Failures in the appropriate production of such hormones may lead to the unregulated changes in plasma glucose and subsequent health problems.

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More Information

Additional Information: Unmapped bibliographic data: M3 - doi: 10.1016/j.mpaic.2013.04.009 [Field not mapped to EPrints]
Depositing User: Marina Sawdon

Identifiers

Item ID: 8126
Identification Number: https://doi.org/10.1016/j.mpaic.2013.04.009
ISSN: 1472-0299
URI: http://sure.sunderland.ac.uk/id/eprint/8126
Official URL: http://dx.doi.org/10.1016/j.mpaic.2013.04.009

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Catalogue record

Date Deposited: 20 Nov 2017 16:21
Last Modified: 20 Nov 2017 16:21

Contributors

Author: Robert Yeo
Author: Marina Sawdon

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