Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.
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Forgham, Helen, Johnson, Darren, Carter, Noel, Veuger, Stephany and Carr-Wilkinson, Jane (2015) Stem Cell Markers in Neuroblastoma—An Emerging Role for LGR5. Frontiers in Cell and Developmental Biology, 3 (77). ISSN 2296-634X
Hunter, J E, Willmore, E, Irving, J A E, Hosomsky, Z, Durkacz, B W and Veuger, Stephany (2012) NF kappaB mediates radiosensitisation by the PARP inhibitor AG-014699. Oncogene, 31 (2). pp. 251-254. ISSN 0950-9232
Mulligan, E, Hunter, J, Baird, A, Elliot, S, Summerfield, G, Parker, C, Veuger, Stephany, Pepper, C, Durkacz, B and Willmore, E (2011) Expression and function of the NFkB subunits in chronic lymphocytic leukaemia : A role for DNA dependent protein kinase in regulating DNA damage activated p65 and p50 subunit activation. Clinical Lymphoma Myeloma and Leukemia, 11 (S2). S167-S168. ISSN 2152-2650
Veuger, Stephany and Durkacz, B W (2011) Persistence of unrepaired DNA double strand breaks caused by inhibition of ATM does not lead to radiosensitisation in the absence of NF kappa B activation. DNA Repair - Responses to DNA damage and other aspects of genomic stability, 10 (2). pp. 235-244. ISSN 1568-7864
Veuger, Stephany, Hunter, J E and Durkacz, B W (2009) Ionizing radiation-induced NF-kappa B activation requires PARP-1 function to confer radioresistance. Oncogene, 28 (6). pp. 832-842. ISSN 0950-9232
Hunter, J E, Hostomsky, Z, Durkacz, B W and Veuger, Stephany (2009) Radio-sensitization by a potent and specific PARP-1 inhibitor is mediated by NF-κB. Proceedings of the American Association for Cancer Research, 1285. ISSN 0569-2261
Veuger, Stephany and Durkacz, B W (2006) DNA repair: therapeutic implications. British Journal of Radiology, 79 (938). pp. 91-93.
Veuger, Stephany and Durkacz, B W (2005) PARP-1 function is essential for resistance to ionising radiation mediated by NFkB activation. Proceedings of the American Association for Cancer research, 2002 (181).
Veuger, Stephany, Curtin, N J, Smith, G C M and Durkacz, B (2004) Effects of novel inhibitors of poly(ADP-ribose)polymerase and the DNA-dependent protein kinase on enzyme activities and DNA repair. Oncogene, 23. pp. 7322-7328.
Veuger, Stephany, Curtin, N J, Richardson, C J, Smith, G C and Durkacz, B W (2003) Radiosentisation and DNA repair inhibition by the combined use of novel inhibitors of DNA dependent protein kinase and poly(ADP-ribose)polymerase-1. Cancer Research, 63 (18). pp. 6008-6015. ISSN 0008-5472
Veuger, Stephany and Curtin, N J (2014) Inhibition of DNA Repair as a Therapeutic Target. In: Cancer Drug Design and Discovery. Elsevier, pp. 193-237. ISBN 9780123965219
Tudthorp, S, Mulligan, E, Hunter, J, Summerfield, S, Marshall, S, Wallis, J, Marr, H, Evans, P, Durkacz, B, Veuger, Stephany, Zhang, J, Meshulam, J, Bobb, J and Willmore, E (2012) PBS-1086, a “pan rel” inhibitor decreases viability of chronic lymphocytic leukaemia cells. In: 54th Annual meeting of the American Society of haematology 2012, 8 - 11 Dec 2012, Atlanta, Georgia.
Mulligan, E, Hunter, J, Baird, A, Elliot, S, Summerfield, G, Hamlen, K, Lowe, C, Wallis, J, Veuger, Stephany, Durkacz, B and Willmore, E (2010) Relationships between aberrant activity of the NFkappaB subunits and outcome in chronic lymphocytic leukaemia. In: BLOOD 52nd Annual meeting of the American Society of Haematology, 4 - 7 Dec 2010, Orange County Convention Center in Orlando, FL, USA.
Hunter, J E, Veuger, Stephany and Durkacz, B W (2008) Inhibition of PARP-1 increases apoptosis and reduces cell survival following IR via NF-κB. In: 17th international symposium on poly(adp-ribosyl)ation. PARP meeting 2008, 28 - 31 May 2008, Loews Ventana Canyon Resort, Tucson, Arizona, USA.