Prevention of medication-related osteonecrosis of the jaw

Sturrock, Andrew, Preshaw, Philip M, Hayes, Catherine and Wilkes, Scott (2019) Prevention of medication-related osteonecrosis of the jaw. The Pharmaceutical Journal, 303 (7928).

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Abstract

Medication-related osteonecrosis of the jaw (MRONJ) is a rare adverse effect of several anti-resorptive and anti-angiogenic drugs that typically presents following a dental extraction. MRONJ is difficult to treat and can have a significant negative effect on quality of life; therefore, the implementation of preventative measures is recommended.

The multidisciplinary healthcare team should work collectively to educate patients on the need for good oral hygiene and ensure that patients undergo remedial dental work prior to the initiation of implicated medicines. As medicine experts, a major aspect of the pharmacist’s role is to educate both patients and other healthcare professionals on the safe and effective use of medicines. Consequently, there is an opportunity for pharmacists working in all settings to contribute to the prevention of MRONJ.

This article provides a summary of the most important background information in relation to the prevention of MRONJ, and outlines the potential opportunities for pharmacists working in community pharmacy, secondary care and general practice.

Item Type: Article
Subjects: Sciences > Pharmacy and Pharmacology
Divisions: Faculty of Health Sciences and Wellbeing
Faculty of Health Sciences and Wellbeing > School of Nursing and Health Sciences
Faculty of Health Sciences and Wellbeing > School of Pharmacy and Pharmaceutical Sciences
Depositing User: Andrew Sturrock
Date Deposited: 29 Aug 2019 10:04
Last Modified: 30 Sep 2020 10:47
URI: http://sure.sunderland.ac.uk/id/eprint/11065
ORCID for Andrew Sturrock: ORCID iD orcid.org/0000-0002-3316-1412
ORCID for Catherine Hayes: ORCID iD orcid.org/0000-0003-3870-2668
ORCID for Scott Wilkes: ORCID iD orcid.org/0000-0003-2949-7711

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