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Cucurull-Sanchez, Lourdes, Chappell, Michael J., Chelliah, Vijayalakshmi, Amy Cheung, S. Y., Derks, Gianne, Penney, Mark, Phipps, Alex, Malik-Sheriff, Rahuman S., Timmis, Jonathan, Tindall, Marcus J., van der Graaf, Piet H., Vicini, Paolo and Yates, James W. T. (2019) Best Practices to Maximize the Use and Reuse of Quantitative and Systems Pharmacology Models: Recommendations From the United Kingdom Quantitative and Systems Pharmacology Network. CPT: Pharmacometrics & Systems Pharmacology, 8 (5). pp. 259-272.

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Abstract

Abstract

The lack of standardization in the way that quantitative and systems pharmacology (QSP) models are developed, tested, and documented hinders their reproducibility, reusability, and expansion or reduction to alternative contexts. This in turn undermines the potential impact of QSP in academic, industrial, and regulatory frameworks. This article presents a minimum set of recommendations from the UK Quantitative and Systems Pharmacology Network (UK QSP Network) to guide QSP practitioners seeking to maximize their impact, and stakeholders considering the use of QSP models in their environment.

Item Type: Article
Depositing User: Jonathan Timmis
URI: https://sure.sunderland.ac.uk/id/eprint/11854

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11854
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Date Deposited
24 Mar 2020 14:09
Last Modified
04 Jun 2025 14:59

Contributors

Author
Lourdes Cucurull-Sanchez
Author
Michael J. Chappell
Author
Vijayalakshmi Chelliah
Author
S. Y. Amy Cheung
Author
Gianne Derks
Author
Mark Penney
Author
Alex Phipps
Author
Rahuman S. Malik-Sheriff
Author
Jonathan Timmis
Author
Marcus J. Tindall
Author
Piet H. van der Graaf
Author
Paolo Vicini
Author
James W. T. Yates

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