Best Practices to Maximize the Use and Reuse of Quantitative and Systems Pharmacology Models: Recommendations From the United Kingdom Quantitative and Systems Pharmacology Network

Cucurull-Sanchez, Lourdes, Chappell, Michael J., Chelliah, Vijayalakshmi, Amy Cheung, S. Y., Derks, Gianne, Penney, Mark, Phipps, Alex, Malik-Sheriff, Rahuman S., Timmis, Jonathan, Tindall, Marcus J., van der Graaf, Piet H., Vicini, Paolo and Yates, James W. T. (2019) Best Practices to Maximize the Use and Reuse of Quantitative and Systems Pharmacology Models: Recommendations From the United Kingdom Quantitative and Systems Pharmacology Network. CPT: Pharmacometrics & Systems Pharmacology, 8 (5). pp. 259-272.

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Abstract

The lack of standardization in the way that quantitative and systems pharmacology (QSP) models are developed, tested, and documented hinders their reproducibility, reusability, and expansion or reduction to alternative contexts. This in turn undermines the potential impact of QSP in academic, industrial, and regulatory frameworks. This article presents a minimum set of recommendations from the UK Quantitative and Systems Pharmacology Network (UK QSP Network) to guide QSP practitioners seeking to maximize their impact, and stakeholders considering the use of QSP models in their environment.

Item Type: Article
Subjects: Computing > Data Science
Sciences > Biomedical Sciences
Sciences > Pharmacy and Pharmacology
Divisions: Faculty of Technology > School of Computer Science
Depositing User: Jonathan Timmis
Date Deposited: 24 Mar 2020 14:09
Last Modified: 24 Mar 2020 14:09
URI: http://sure.sunderland.ac.uk/id/eprint/11854

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