In vitro physicochemical characterization of nanocarriers: a road to optimization

Goel, Honey, Saini, Komal, Razdan, Karan, Khurana, Rajneet Kaur, Elkordy, Amal and Singh, Kamalinder K. (2021) In vitro physicochemical characterization of nanocarriers: a road to optimization. In: Nanoparticle Therapeutics Production Technologies, Types of Nanoparticles, and Regulatory Aspects. Elsevier, pp. 133-180. ISBN 9780128207574

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Abstract

Today's drug delivery scientists and pharmaceutical technologists own unprecedented variety of characterization techniques at their disposal not only to assign precise numerical values to the particle parameters but also to probe their developmental phases as well as their internal environment. Therefore, mechanistic understanding of structure-function relationships of nanotherapeutic systems seems to be a dynamic avowal considering the optimization of final nanoformulation system intended for biodistribution and targeting. This chapter aims to decipher the key in vitro physicochemical parameters in dry state, liquid state, as well as in both dry and liquid states, with the perspective of nanoparticle technology, and the diverse physical and experimental means in which these parameters can be demarcated. Further, an attempt has been made to introduce some best suited specialized techniques that enable to expand the accessible range of information to gain deeper insights into specific nanoplatform properties.

Item Type: Book Section
Subjects: Sciences > Pharmacy and Pharmacology
Divisions: Faculty of Health Sciences and Wellbeing
Depositing User: Amal Elkordy
Date Deposited: 26 Nov 2021 11:49
Last Modified: 26 Nov 2021 11:49
URI: http://sure.sunderland.ac.uk/id/eprint/14180

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