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Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

Application of approved and marketed products of monoclonal antibody therapies

Elkordy, Amal, Elsayed, Moustafa, Al-Abdulrazag, Sohib Bashier and Zarara, Zeinab Moataz (2023) Application of approved and marketed products of monoclonal antibody therapies. In: Formulation of Monoclonal Antibody Therapies: From Lab to Market. Elsevier, pp. 287-327. ISBN 9780128233658

Item Type: Book Section


Monoclonal antibody (mAb)-based therapies are highly specific and effective for a particular antigen. This unique characteristic feature of the mAb makes them ideal candidates for various applications not limited to oncology and immune diseases but also asthma, inflammatory diseases, infections, migraine as well as hematology and eye diseases. Moreover, mAbs have been applied in new areas including dentistry, tackling COVID-19 (SARS-CoV-2) pandemic and in July 30, 2021, nifrolumab-fnia has been granted FDA approval for the treatment of adult patients with moderate to severe systemic lupus erythematosus. Before then and on June 7, 2021, the FDA approved aducanumab for the treatment of Alzheimer disease.

Accordingly, this chapter will cover the application and clinical uses of mAbs with examples for market products. Also, it will cover the current market of mAbs and their market in the future based on both the clinical trials of mAbs formulations and new areas for application of the mAbs.

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More Information

Depositing User: Amal Elkordy


Item ID: 16202
ISBN: 9780128233658
Official URL:

Users with ORCIDS

ORCID for Amal Elkordy: ORCID iD

Catalogue record

Date Deposited: 01 Jun 2023 16:40
Last Modified: 01 Jun 2023 16:40


Author: Amal Elkordy ORCID iD
Author: Moustafa Elsayed
Author: Sohib Bashier Al-Abdulrazag
Author: Zeinab Moataz Zarara

University Divisions

Faculty of Health Sciences and Wellbeing > School of Pharmacy and Pharmaceutical Sciences


Sciences > Pharmacy and Pharmacology

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