Neves-Marques, Claudia, Abouelazayem, Mohamed, Gupte, Anaya, Mun Wong, Geoffrey Yuet, Vish, Y K S, Boddy, Alex, Donohue, Claire, Maldonado, Ricardo David, Scarano, Juan Pablo, Martinino, Alessandro, Aamery, Amaar, Abdulkhakimov, Nuriddin, Abuobaida, Essam Eldien, Aday, Ulaş, Al-Shami, Khayry, Alhajami, Faris, Almeida, Ana, Ahmed, Hassan, Andrada, Martín, Anwer, Abdul Wahid, Awad, Ahmed, Badr, Mohammad, Baili, Efstratia, Baraket, Oussama, Barbosa, José, Baker, Cara, Bakri, Ashraf, Boras, Zdenko, Caiado, André, Cayirci, Can, Calini, Giacomo, Cianci, Pasquale, Cinal, Esin, Chouliaras, Christos, Colak, Elif, Correia, Maria Teresa, Costeira, Beatriz, Davletshina, Viktoria, D’Acapito, Fabrizio, Donmez, Turgut, Drozdov, Evgeniy, Ercolani, Giorgio, Erdene, Sarnai, Erginöz, Ergin, Ferreira, Samantha Rocha, Fragoso, Marta, Framarini, Massimo, Galandarova, Aysuna, Genser, Laurent, Gorohov, Ilya, Grosek, Jan, Guerrero, Silvia, Hasırcı, Ismail, Ibrahimli, Arturan, Ithurralde-Argerich, Javier, Karabulut, Mehmet, Kinoshita, Takahiro, Khalid, Ibtissam Bin, Khan, Khurram, Khattak, Shahid, Khomyakov, Vladimir, Krawczyk, Wiktor, Kostrygin, Alexander, Košir, Jurij, Lorenc, Zbigniew, Milhomem, Jorge, Marom, Gadi, Melo, Ana, Menasria, Abdelkader, Meric, Serhat, Mulita, Francesk, Muratore, Andrea, Omarov, Taryel, Palomba, Giuseppe, Paul, Negine, Pathak, Akshant, Pavone, Giovanna, Pavlov, Rostislav, Pinillla, Raul, Rasheed, Omeed, Remini, Anouar, Ryabov, Andrey, Samadov, Elgun, Samarasam, Inian, Santos, Jorge, Sanchez, Elio, Saroglu, Azize, Schizas, Dimitrios, Serralheiro, Pedro, Simsek, Oguzhan, Sobolev, Dmitry, Souadka, Amine, Sousa, José, Sousa, Fabiana, Suer, Muhammed, Surendran, Suraj, Syllaios, Athanasios, Syed, Aamir Ali, Terajima, Daiki, Tokocin, Merve, Triantafyllou, Tania, Uludağ, Server, Uprak, Tevfik, Vaz, Susan, Vecchiato, Massimo, Verras, Georgios Ioannis, Veroux, Massimiliano, Voon, Kelvin, Vovin, Kirill, Yacob, Myla, Walędziak, Maciej, Zacharenko, Alexander, Zahara, Fatima Tu, Singhal, Rishi and Mahawar, Kamal (2024) OGC O01 - Stomach Cancer Elective Surgery Morbidity and Mortality at 90-Days (HOLD Study): A Prospective, International Collaborative Cohort Study. British Journal of Surgery, 111 (Supple). ix5. ISSN 1365-2168
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Abstract
Abstract
Background
Data on multinational 90-day mortality and morbidity rates after surgery for gastric cancer is limited in the literature. This study aimed to understand the 90-day mortality and morbidity outcomes according to GASTRODATA Registry for elective gastric cancer surgery patients and identify risk factors.
Method
We conducted an international prospective study on ≥18 years patients undergoing elective surgery for gastric cancer with curative intent from 01 April 2022 to 30 September 2022. Known metastatic disease, concurrent secondary cancers, gastrointestinal stromal tumour (GIST) and Siewert type I/II oesophagogastric junction malignancies were excluded. Univariate and multivariate logistic regression was used to identify variables associated to 90-day outcome.
Results
380 collaborators from 47 countries submitted data on 1538 patients. Mean age was 64.2 years and 58.5% were males. 90-day morbidity rate was 38.2% (n=587) and mortality rate was 2.9% (n=45).
Pre-operative higher CCI or ASA score, pre-operative weight loss >10%, and surgical determinants such as type of gastric resection, positive specimen margin, number of harvested lymph nodes, longer surgery duration and post operative pathological IV staging (p value<0.05) were identified as predictors of postoperative severe complications and mortality.
Conclusion
Elective gastric cancer surgery has a 90-day morbidity of 38.2% and 90-day mortality of 2.9%, globally. This study identified several factors associated with higher morbidity and exemplified the importance of a unified language on surgical morbidity, pre-habilitation and ongoing audits to enhance patient outcomes.
| Item Type: | Article |
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| Additional Information: | Volume 111, Issue Supplement_9, November 2024 Abstracts of the 27th AUGIS Annual Scientific Meeting Bridgewater Hall & Midland Hotel, Manchester 11–13 September 2024 ** Article version: VoR ** From Crossref journal articles via Jisc Publications Router ** History: epub 13-11-2024; ppub 13-11-2024. ** Licence for VoR version of this article starting on 01-11-2024: https://academic.oup.com/pages/standard-publication-reuse-rights |
| Uncontrolled Keywords: | weight reduction cancer gastrectomy gastric cancer esophagogastric junction financial audit languages neoplasm metastasis surgical procedures, elective surgical procedures, operative lymph nodes morbidity mortality gastrointestinal stromal tumor patient-focused outcomes habilitation |
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| SWORD Depositor: | Publication Router |
| Depositing User: | Publication Router |
| URI: | https://sure.sunderland.ac.uk/id/eprint/18503 |
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