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Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

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Number of items: 34.

Bedernjak, Alexandre, Zaytsev, A.V., Babolat, M., Cellier, M., James, A.L., Orenga, S., Perry, J.D., Groundwater, Paul and Anderson, Rosaleen (2016) Synthesis and evaluation of novel 7- and 8-aminophenoxazinones for the detection of β-alanine aminopeptidase activity and the rapid identification of Pseudomonas aeruginosa in clinical samples. Journal of Medicinal Chemistry, 59 (10). pp. 4476-4487. ISSN 0022-2623

Bedernjak, Alexandre, Groundwater, Paul, Gray, Mark, Orenga, S, Perry, J D and Anderson, Rosaleen (2013) Synthesis and evaluation of halogenated nitrophenoxazinones as nitroreductase substrates for the detection of pathogenic bacteria. Tetrahedron, 69 (39). pp. 8456-8462. ISSN 0040-4020

George, S. E., Anderson, Rosaleen, Haswell, M and Groundwater, Paul (2013) An investigation of the effects of dithranol-induced apoptosis in a human keratinocyte cell line. Journal of Pharmacy and Pharmacology, 65 (4). pp. 552-560. ISSN 2042-7158

P90448WO (2012) Melatonin Derivatives and their Uses as Antioxidants. US0828173.

Anderson, Rosaleen, Groundwater, Paul, Todd, Adam and Worsley, Alan (2012) Antibacterial agents: chemistry, mode of action, mechanisms of resistance and clinical applications. Wiley Blackwell. ISBN ISBN: 978-0-470-97245-8

George, Suja, Anderson, Rosaleen, Hambleton, Paul and Groundwater, Paul (2012) A simple RP-HPLC method for the determination of the anti-psoriatic drug dithranol and its application in an in vitro cell uptake study. Current Pharmaceutical Analysis, 8 (1). pp. 75-82. ISSN 1573-4129

Patent No. PCT/FR05/02249 (WO 2006/030119), 23/03/2006; (2012) Nouveaux Substrats Enzymatiques Dérivés de Phénoxazinone et leur Utilisation comme Révélateur dans la Détection de Micro-organismes à Activité Peptidase. EP 1786828 B1.

Kottakota, S K, Evangelopoulos, D, Alnimr, A, Bhakta, S, McHugh, T, Gray, Mark, Groundwater, Paul, Marrs, E C L, Perry, J D, Spilling, C D and Harburn, J J (2012) Synthesis and Biological Evaluation of Purpurealidin E-Derived Marine Sponge Metabolites: Aplysamine-2, Aplyzanzine A, and Suberedamines A and B. Journal of Natural Products, 75 (6). pp. 1090-1101. ISSN 0163-3864

Varadi, Linda, Gray, Mark, Groundwater, Paul, Hall, Andrew, James, Arthur L, Orenga, Sylvain, Perry, John D and Anderson, Rosaleen (2012) Synthesis and evaluation of fluorogenic 2-amino-1,8-naphthyridine derivatives for the detection of bacteria. Organic & Biomolecular Chemistry, 10 (13). pp. 2578-2589. ISSN 1477-0520

Frost, Lisa, Auckland, C, Khaw, C, Mankarous, M, Small, Andrea, Otun, Joy, Thynne, Barrie, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for ocular treatment of cystinosis. In: Cystinosis Foundation UK Conference, 24 Sept 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Frost, Lisa, Auckland, C, Khaw, C, Mankarous, M, Small, Andrea, Otun, Joy, Thynne, Barrie, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for ocular treatment of cystinosis. In: Cystinosis Research Network 2011 Family Conference, 14 July 2011, Hotel Nikko, San Francisco, CA. (Unpublished)

Frost, Lisa, Cannell, Stephanie, Suryadevara, P, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for an improved treatment of cystinosis. In: Cystinosis Research Network 2011 Family Conference, 14 July 2011, Hotel Nikko, San Francisco, CA. (Unpublished)

Frost, Lisa, Cannell, Stephanie, Suryadevara, P, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for an improved treatment of cystinosis. In: Cystinosis Foundation UK Conference, 24 Sept 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Marth, Gabriella, Anderson, Rosaleen, Thompson, Barry G, Ashton, Mark and Groundwater, Paul (2010) Chemo- and regioselectivity in the reactions of polyfunctional pyrroles. Tetrahedron, 66 (32). pp. 6113-6120. ISSN 0040-4020

Todd, Adam, Anderson, Rosaleen, Groundwater, Paul and George, Suja (2010) Current and potential new therapies for the treatment of psoriasis. The Pharmaceutical Journal, 284. pp. 560-561. ISSN 0031-68176

George, Suja, Anderson, Rosaleen, Cunningham, Anne, Donaldson, M and Groundwater, Paul (2010) Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay. ASSAY and Drug Development Technologies, 8 (3). pp. 384-395. ISSN 1540-658X

Todd, Adam, Anderson, Rosaleen, Pickles, Grace and Groundwater, Paul (2010) Targeting the thioredoxin system in the treatment of certain cancers. The Pharmaceutical Journal, 284. pp. 243-244. ISSN 0031-6873

Williamson, Steve, Todd, Adam, Anderson, Rosaleen and Groundwater, Paul (2010) Current advances and research in the treatment of pancreatic cancer. The Pharmaceutical Journal, 284. pp. 137-138. ISSN 0031-6873

Ning, Fuquiang, Anderson, Rosaleen, Hibbs, David E and Groundwater, Paul (2010) A new, one-step synthesis of 1-heteroaryl-2-alkylaminoethanols. Tetrahedron Letters, 51 (5). pp. 843-850. ISSN 0040-4039

Kottakota, Suresh, Harburn, Jonathan, Guzman, J, Bhakta, S, Gray, Mark and Groundwater, Paul (2010) Synthesis of 20-N-methylpurpuramine E, an antitubercural metabolite from pseudoceratina sponge; paper no. b021. In: Proceedings of ECSOC-14, The Fourteenth International Electronic Conference on Synthetic Organic Chemistry. Sciforum Electronic Conferences Series . MDPI, Basel, Switzerland, pp. 1-9. ISBN 3-906980-24-3

Anderson, Rosaleen, Groundwater, Paul, Moore, Adrian and Todd, Adam (2009) An overview of cancer treatments. The Pharmaceutical Journal, 283. pp. 511-512. ISSN 0031-6873

Todd, Adam, Worsley, Alan, Anderson, Rosaleen and Groundwater, Paul (2009) Current research and development into new antibacterial agents. The Pharmaceutical Journal, 283. pp. 359-360. ISSN 0031-6873

Groundwater, Paul, Worsley, Alan, Anderson, Rosaleen and Todd, Adam (2009) The technology and techniques used in the detection of pathogenic bacteria. The Pharmaceutical Journal, 283. pp. 281-282. ISSN 0031-6873

Todd, Adam, Anderson, Rosaleen and Groundwater, Paul (2009) Rational drug design - designing a molecule that binds to a target. The Pharmaceutical Journal, 283. pp. 131-132. ISSN 0031-6873

Todd, Adam, Anderson, Rosaleen and Groundwater, Paul (2009) Rational drug design — identifying and characterising a target. The Pharmaceutical Journal, 283. pp. 19-20. ISSN 0031-6873

Zaytsev, Andrey V, Anderson, Rosaleen, Bedernjak, Alexandre, Groundwater, Paul, Huang, Yongxue and Perry, John D (2008) Synthesis and testing of chromogenic phenoxazinone substrates for β-alanyl aminopeptidase. Organic and Biomolecular Chemistry, 6 (4). pp. 682-692. ISSN 1477-0520

Anderson, Rosaleen, Groundwater, Paul, Huang, Yongxue, James, Arthur L, Orenga, Sylvain, Rigby, A, Roger-Dalbert, C and Perry, John D (2008) Synthesis and evaluation of novel chromogenic peptidase substrates based on 9-(4'-Aminophenyl)- 10 methylacridinium salts as diagnostic tools in clinical bacteriology. Bioorganic & Medicinal Chemistry Letters, 18 (2). pp. 832-835. ISSN 0960-894X

Anderson, Rosaleen, Cairns, Donald, Groundwater, Paul and Meth-Cohn, Otto (2006) Design, Synthesis and Initial in vitro Evaluation of Novel Prodrugs for the Treatment of Cystinosis. Letters in Drug Design & Discovery, 3 (5). pp. 336-345. ISSN 15701808

Dodou, Kalliopi and Groundwater, Paul (2005) Psoriasis sufferers get new hope. BBC News.

Groundwater, Paul, Dodou, Kalliopi, Anderson, Rosaleen and Lough, John (2005) Synthesis of gossypol atropisomers and derivatives and evaluation of their anti-proliferative and anti-oxidant activity. Bioorg. Med. Chem., 13 (13). pp. 4228-4237. ISSN 09680896

Groundwater, Paul, Nyerges, Miklos, Bendell, David, Arany, Andrea and Meth-Cohn, Otto (2003) Silver Acetate Catalysed Asymmetric 1,3-Dipolar Cycloadditions of Imines and Chiral Acrylamides. SynLett, 7. pp. 947-950. ISSN 09365214

Groundwater, Paul, Nyerges, Miklos, Arany, Andrea, Fejes, Imres and Anderson, Rosaleen (2002) The Generation and Reactivity of N-Substituted, Stabilised alpha,beta:gamma,delta-Unsaturated Azomethine Ylides. Tetrahedron, 58 (5). pp. 989-995. ISSN 00404020

Anderson, Rosaleen, Bendell, David, Garnett, Ian, Groundwater, Paul, Lough, John and Shattock, Paul (2002) Identification of Indolyl-3-acryloylglycine (IAcrGly) in the Urine of People with Autism. Journal of Pharmacy and Pharmacology, 54 (2). pp. 295-298. ISSN 00223573

Groundwater, Paul, Nyerges, Miklos, Fejes, Imre and Viranyi, Andrea (2001) A New and Convenient Synthesis of 1-Aryl-2-dimethylaminoethanols. Synthesis, 10. pp. 1479-1482. ISSN 00397881

This list was generated on Thu Apr 18 05:28:28 2024 BST.