SURE

Article

Ng, Keng Tiong, Perry, John D., Marrs, Emma C.L., Orenga, Sylvain, Anderson, Rosaleen and Gray, Mark (2020) Synthesis and Antimicrobial Activity of Phosphonopeptide Derivatives Incorporating Single and Dual Inhibitors. Molecules, 25 (7). e1557. ISSN 1420-3049

Marrs, Emma C.L., Varadi, Linda, Bedernjak, Alexandre F., Day, Kathryn M., Gray, Mark, Jones, Amanda L., Cummings, Stephen P., Anderson, Rosaleen and Perry, John D. (2020) Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance. Molecules, 25 (6). e1445. ISSN 1420-3049

Kondacs, Laszlo A., Orenga, Sylvain, Anderson, Rosaleen, Marrs, Emma C.L., Perry, John D. and Gray, Mark (2020) C-Terminal 1-Aminoethyltetrazole-Containing Oligopeptides as Novel Alanine Racemase Inhibitors. Molecules, 25 (6). e1315. ISSN 1420-3049

Said Suliman, Ammar, Anderson, Rosaleen and Elkordy, Amal (2019) Preparation of novel optimum liquisolid compacts via incorporating water granulation process to enhance the powder characterizations and dissolution behavior of a poorly soluble drug: Norfloxacin. Powder Technology. ISSN 0032-5910

Varadi, Linda, Luo, Jia Lin, Hibbs, David E., Perry, John D., Anderson, Rosaleen, Orenga, Sylvain and Groundwater, Paul W. (2017) Methods for the detection and identification of pathogenic bacteria: past, present, and future. Chemical Society Reviews, 46 (16). pp. 4818-4832. ISSN 0306-0012

Bedernjak, Alexandre, Zaytsev, A.V., Babolat, M., Cellier, M., James, A.L., Orenga, S., Perry, J.D., Groundwater, Paul and Anderson, Rosaleen (2016) Synthesis and evaluation of novel 7- and 8-aminophenoxazinones for the detection of β-alanine aminopeptidase activity and the rapid identification of Pseudomonas aeruginosa in clinical samples. Journal of Medicinal Chemistry, 59 (10). pp. 4476-4487. ISSN 0022-2623

Frost, Lisa, Suryadevara, Pratap, Cannell, Stephanie, Groundwater, Paul, Hambleton, Paul and Anderson, Rosaleen (2015) Synthesis of diacylated γ-glutamyl-cysteamine prodrugs, and in vitro evaluation of their cytotoxicity and intracellular delivery of cysteamine. European Journal of Medicinal Chemistry, 109. pp. 206-215. ISSN 0009-4374

Zhang, Weimin, Ning, Fuquiang, Varadi, Linda, Hibbs, David E., Platts, James A., Nyerges, Miklos, Anderson, Rosaleen and Groundwater, Paul (2014) An investigation of the scope of the 1,7-electrocyclization of α,b:γ,δ-conjugated azomethine ylides. Tetrahedron, 70 (22). pp. 3621-3629. ISSN 0040-4020

Said Suliman, Ammar, Anderson, Rosaleen and Elkordy, Amal (2014) Norfloxacin as a model hydrophobic drug with unique release from liquisolid formulations prepared with PEG200 and Synperonic PE/L-61 non-volatile liquid vehicles. Powder Technology, 257. pp. 156-167. ISSN 0032-5910

Bedernjak, Alexandre, Groundwater, Paul, Gray, Mark, Orenga, S, Perry, J D and Anderson, Rosaleen (2013) Synthesis and evaluation of halogenated nitrophenoxazinones as nitroreductase substrates for the detection of pathogenic bacteria. Tetrahedron, 69 (39). pp. 8456-8462. ISSN 0040-4020

Alderton, W K, Anderson, Rosaleen, Collingwood, S P and Pryde, D C (2013) Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, London, UK. Drugs of the Future, 38 (5). p. 347. ISSN 0377-8282

George, S. E., Anderson, Rosaleen, Haswell, M and Groundwater, Paul (2013) An investigation of the effects of dithranol-induced apoptosis in a human keratinocyte cell line. Journal of Pharmacy and Pharmacology, 65 (4). pp. 552-560. ISSN 2042-7158

Petch, Donna, Anderson, Rosaleen, Cunningham, Anne, George, S E, Hibbs, D E, Liu, R, Mackay, S P, Paul, A, Small, D A P and Groundwater, P W (2012) Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis. Bioorganic & Medicinal Chemistry, 20 (19). pp. 5901-5914. ISSN 0968-0896

George, Suja, Anderson, Rosaleen, Hambleton, Paul and Groundwater, Paul (2012) A simple RP-HPLC method for the determination of the anti-psoriatic drug dithranol and its application in an in vitro cell uptake study. Current Pharmaceutical Analysis, 8 (1). pp. 75-82. ISSN 1573-4129

Varadi, Linda, Gray, Mark, Groundwater, Paul, Hall, Andrew, James, Arthur L, Orenga, Sylvain, Perry, John D and Anderson, Rosaleen (2012) Synthesis and evaluation of fluorogenic 2-amino-1,8-naphthyridine derivatives for the detection of bacteria. Organic & Biomolecular Chemistry, 10 (13). pp. 2578-2589. ISSN 1477-0520

Marth, Gabriella, Anderson, Rosaleen, Thompson, Barry G, Ashton, Mark and Groundwater, Paul (2010) Chemo- and regioselectivity in the reactions of polyfunctional pyrroles. Tetrahedron, 66 (32). pp. 6113-6120. ISSN 0040-4020

Todd, Adam, Anderson, Rosaleen, Groundwater, Paul and George, Suja (2010) Current and potential new therapies for the treatment of psoriasis. The Pharmaceutical Journal, 284. pp. 560-561. ISSN 0031-68176

George, Suja, Anderson, Rosaleen, Cunningham, Anne, Donaldson, M and Groundwater, Paul (2010) Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay. ASSAY and Drug Development Technologies, 8 (3). pp. 384-395. ISSN 1540-658X

Todd, Adam, Anderson, Rosaleen, Pickles, Grace and Groundwater, Paul (2010) Targeting the thioredoxin system in the treatment of certain cancers. The Pharmaceutical Journal, 284. pp. 243-244. ISSN 0031-6873

Williamson, Steve, Todd, Adam, Anderson, Rosaleen and Groundwater, Paul (2010) Current advances and research in the treatment of pancreatic cancer. The Pharmaceutical Journal, 284. pp. 137-138. ISSN 0031-6873

Ning, Fuquiang, Anderson, Rosaleen, Hibbs, David E and Groundwater, Paul (2010) A new, one-step synthesis of 1-heteroaryl-2-alkylaminoethanols. Tetrahedron Letters, 51 (5). pp. 843-850. ISSN 0040-4039

Anderson, Rosaleen, Groundwater, Paul, Moore, Adrian and Todd, Adam (2009) An overview of cancer treatments. The Pharmaceutical Journal, 283. pp. 511-512. ISSN 0031-6873

Todd, Adam, Worsley, Alan, Anderson, Rosaleen and Groundwater, Paul (2009) Current research and development into new antibacterial agents. The Pharmaceutical Journal, 283. pp. 359-360. ISSN 0031-6873

Groundwater, Paul, Worsley, Alan, Anderson, Rosaleen and Todd, Adam (2009) The technology and techniques used in the detection of pathogenic bacteria. The Pharmaceutical Journal, 283. pp. 281-282. ISSN 0031-6873

Todd, Adam, Anderson, Rosaleen and Groundwater, Paul (2009) Rational drug design - designing a molecule that binds to a target. The Pharmaceutical Journal, 283. pp. 131-132. ISSN 0031-6873

Todd, Adam, Anderson, Rosaleen and Groundwater, Paul (2009) Rational drug design — identifying and characterising a target. The Pharmaceutical Journal, 283. pp. 19-20. ISSN 0031-6873

Zaytsev, Andrey V, Anderson, Rosaleen, Bedernjak, Alexandre, Groundwater, Paul, Huang, Yongxue and Perry, John D (2008) Synthesis and testing of chromogenic phenoxazinone substrates for β-alanyl aminopeptidase. Organic and Biomolecular Chemistry, 6 (4). pp. 682-692. ISSN 1477-0520

Anderson, Rosaleen, Groundwater, Paul, Huang, Yongxue, James, Arthur L, Orenga, Sylvain, Rigby, A, Roger-Dalbert, C and Perry, John D (2008) Synthesis and evaluation of novel chromogenic peptidase substrates based on 9-(4'-Aminophenyl)- 10 methylacridinium salts as diagnostic tools in clinical bacteriology. Bioorganic & Medicinal Chemistry Letters, 18 (2). pp. 832-835. ISSN 0960-894X

Anderson, Rosaleen, Cairns, Donald, Groundwater, Paul and Meth-Cohn, Otto (2006) Design, Synthesis and Initial in vitro Evaluation of Novel Prodrugs for the Treatment of Cystinosis. Letters in Drug Design & Discovery, 3 (5). pp. 336-345. ISSN 15701808

Groundwater, Paul, Dodou, Kalliopi, Anderson, Rosaleen and Lough, John (2005) Synthesis of gossypol atropisomers and derivatives and evaluation of their anti-proliferative and anti-oxidant activity. Bioorg. Med. Chem., 13 (13). pp. 4228-4237. ISSN 09680896

Groundwater, Paul, Nyerges, Miklos, Arany, Andrea, Fejes, Imres and Anderson, Rosaleen (2002) The Generation and Reactivity of N-Substituted, Stabilised alpha,beta:gamma,delta-Unsaturated Azomethine Ylides. Tetrahedron, 58 (5). pp. 989-995. ISSN 00404020

Anderson, Rosaleen, Bendell, David, Garnett, Ian, Groundwater, Paul, Lough, John and Shattock, Paul (2002) Identification of Indolyl-3-acryloylglycine (IAcrGly) in the Urine of People with Autism. Journal of Pharmacy and Pharmacology, 54 (2). pp. 295-298. ISSN 00223573

Anderson, Rosaleen, Bendell, David, Hooper, Malcolm, Cairns, Donald and Mackay, Simon Paul (2001) Potential Transition State Phosphoramidate Inhibitors of beta-Tubulin as Anti-Filarial Agents. Journal of Pharmacy and Pharmacology, 53 (1). pp. 89-94. ISSN 00223573

Book Section

Anderson, Rosaleen and Todd, Adam (2013) Stereochemistry and Drug Action. In: Pharmaceutical Chemistry. Integrated Foundations of Pharmacy . Oxford University Press, Oxford. ISBN 978-0-19-965530-4

Conference or Workshop Item

Amer, Amer H., Anderson, Rosaleen, Carlile, Mark, Dawson, Peter and Ashton, Mark (2017) A 3D-QSAR Pharmacophore based virtual screening and docking approach to identify novel HIV-1 entry inhibitors. In: New Approaches in Medicinal Chemistry II, 01 Feb 2017, Eli Lilly, Windlesham, UK. (Unpublished)

Anderson, Rosaleen (2016) Developing a targeted treatment: Where are we now? In: Second Cystinosis Foundation Ireland Scientific Workshop, 1-2 Apr 2016, The Pillo Hotel, Ashbourne, Dublin, Ireland. (Unpublished)

Anderson, Rosaleen (2016) Developing an improved treatment for cystinosis: the prodrug project. In: International Cystinosis Conference, 30 June - 3 July 2016, Valencia, Spain. (Unpublished)

Dawson, Peter, Jobson, Jill, Carter, Noel, Treumann, A., McGarry, Kenneth and Anderson, Rosaleen (2016) Investigating the protein differences between cystinotic and non-cystinotic cells. In: International Cystinosis Conference, 30 June - 3 July 2016, Valencia, Spain. (Submitted)

Frost, Lisa, Hambleton, Paul and Anderson, Rosaleen (2016) A cysteamine prodrug to improve the treatment of cystinosis. In: International Cystinosis Conference, 30 June - 3 July 2016, Valencia, Spain. (Unpublished)

Anderson, Rosaleen (2015) Suicide substrates for pathogen identification in clinical diagnostics. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Submitted)

McMahon, Fiona, Dawson, Peter, Anderson, Rosaleen, Sattelle, Ben, Warrender, Robert and Gray, Mark (2015) Development of Functional Computational Workflow Methods for Quality Automated Molecular Modelling-based Drug Design. In: MGMS Young Modellers Forum 2015, 27 Nov 2015, Greenwich, London. (Submitted)

Suliman, A.S., Anderson, Rosaleen and Elkordy, Amal (2015) Liquisolid technique in combination with wet granulation process for improving norfloxacin dissolution. In: Formulation and Drug Delivery Conference 2015, 18-19 May 2015, Kensington Close Hotel, London, UK. (Unpublished)

Anderson, Rosaleen (2014) Prodrugs and Proteins. In: International Cystinosis Congress 2014, 24 - 27 July 2014, Manchester, UK.

Anderson, Rosaleen (2013) News from the North: new developments in cystinosis research. In: National Study Day: Update on Care of Patients with Cystinosis, 1st October 2013, Queen Elizabeth Hospital, Birmingham (UK)..

Suliman, A S, Anderson, Rosaleen and Elkordy, Amal (2013) Liquisolid Tablet Preparation for Norfloxacin Dissolution Enhancement. In: UK-PharmSci 2013 conference,, 2 - 4 Sep 2013, Edinburgh, UK..

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, A and Anderson, Rosaleen (2013) A Quantitative Proteomic Investigation of Cystinotic Fibroblasts and Proximal Tubule Epithelial Cells using SILAC. In: Cystinosis Research Network Conference, 18 - 20 Jul 2013, Washington D.C., USA.

Anderson, Rosaleen (2012) Improving the Treatment of Cystinosis. In: Advances in Clinical Analysis 2012, RSC Separation Sciences Group / Chromatographic Society Conference, 30 Oct 2012, Guys Hospital Tower, London.

Fox, Charlotte, Husband, Andy, Anderson, Rosaleen, Ling, Jonathan, Williamson, S and Todd, Adam (2012) Genotypic Variation and Chemotherapy induced nausea and vomiting. In: British Oncology Pharmacist Association (BOPA) Conference. 15th Annual Symposium, 19 - 21 Oct 2012, Harrogate International Centre, Harrogate, UK.

Anderson, Rosaleen (2012) Improving the Treatment of Cystinosis. In: 7th International Cystinosis Conference, 28 Jun - 01 Jul 2012, Paris, France.

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, A and Anderson, Rosaleen (2012) A Quantitative Proteomic Comparison of Cystinotic and Control Fibroblasts. In: 7th International Cystinosis Conference, 28 June – 01 July 2012, Marriott Charles de Gaulle Hotel, Paris, France.

Frost, Lisa, Auckland, C, Khaw, C, Mankarous, M, Small, Andrea, Otun, Joy, Thynne, Barrie, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for ocular treatment of cystinosis. In: Cystinosis Foundation UK Conference, 24 Sept 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Anderson, Rosaleen (2011) Cysteamine prodrugs for the improved treatment of cystinosis. In: Cystinosis Foundation UK Conference, 24 Sep 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, Achim and Anderson, Rosaleen (2011) Proteomic investigation of cystinotic cells and the effects of cysteamine treatment. In: Cystinosis Foundation UK Conference, 24 Sept 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Frost, Lisa, Auckland, C, Khaw, C, Mankarous, M, Small, Andrea, Otun, Joy, Thynne, Barrie, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for ocular treatment of cystinosis. In: Cystinosis Research Network 2011 Family Conference, 14 July 2011, Hotel Nikko, San Francisco, CA. (Unpublished)

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, Achim and Anderson, Rosaleen (2011) Proteomic investigation of cystinotic cells and the effects of cysteamine treatment. In: Cystinosis Research Network 2011 Family Conference, 14 July 2011, Hotel Nikko, San Francisco, CA. (Unpublished)

Anderson, Rosaleen (2011) Cystinosis - a Rare Opportunity. In: Royal Society of Chemistry(RSC) Organic Division Northeast Region Symposium, 13 Apr 2011, Northumbria University, UK. (Unpublished)

Frost, Lisa, Cannell, Stephanie, Suryadevara, P, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for an improved treatment of cystinosis. In: Cystinosis Research Network 2011 Family Conference, 14 July 2011, Hotel Nikko, San Francisco, CA. (Unpublished)

Frost, Lisa, Cannell, Stephanie, Suryadevara, P, Hambleton, Paul, Groundwater, Paul and Anderson, Rosaleen (2011) Cysteamine prodrugs for an improved treatment of cystinosis. In: Cystinosis Foundation UK Conference, 24 Sept 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Book

Anderson, Rosaleen, Groundwater, Paul, Todd, Adam and Worsley, Alan (2012) Antibacterial agents: chemistry, mode of action, mechanisms of resistance and clinical applications. Wiley Blackwell. ISBN ISBN: 978-0-470-97245-8

Patents

BIOMÉRIEUX (2019) Antibacterial compound and use of same. WO/2019/058074.

P90448WO (2012) Melatonin Derivatives and their Uses as Antioxidants. US0828173.

Patent No. PCT/FR05/02249 (WO 2006/030119), 23/03/2006; (2012) Nouveaux Substrats Enzymatiques Dérivés de Phénoxazinone et leur Utilisation comme Révélateur dans la Détection de Micro-organismes à Activité Peptidase. EP 1786828 B1.