Close menu

SURE

Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

High estradiol levels improve false memory rates and meta-memory in highly schizotypal women

Hodgetts, Sophie, Hausmann, Markus and Weis, Susanne (2015) High estradiol levels improve false memory rates and meta-memory in highly schizotypal women. Psychiatry Research, 229 (3). pp. 708-714. ISSN 0165-1781

Item Type: Article

Abstract

Overconfidence in false memories is often found in patients with schizophrenia and healthy participants with high levels of schizotypy, indicating an impairment of meta-cognition within the memory domain. In general, cognitive control is suggested to be modulated by natural fluctuations in oestrogen. However, whether oestrogen exerts beneficial effects on meta-memory has not yet been investigated. The present study sought to provide evidence that high levels of schizotypy are associated with increased false memory rates and overconfidence in false memories, and that these processes may be modulated by natural differences in estradiol levels. Using the Deese-Roediger-McDermott paradigm, it was found that highly schizotypal participants with high estradiol produced significantly fewer false memories than those with low estradiol. No such difference was found within the low schizotypy participants. Highly schizotypal participants with high estradiol were also less confident in their false memories than those with low estradiol; low schizotypy participants with high estradiol were more confident. However, these differences only approached significance. These findings suggest that the beneficial effect of estradiol on memory and meta-memory observed in healthy participants is specific to highly schizotypal individuals and might be related to individual differences in baseline dopaminergic activity.

[img]
Preview
PDF
16189.pdf - Accepted Version

Download (289kB) | Preview

More Information

Depositing User: Sophie Hodgetts

Identifiers

Item ID: 8680
Identification Number: https://doi.org/10.1016/j.psychres.2015.08.016
ISSN: 0165-1781
URI: http://sure.sunderland.ac.uk/id/eprint/8680
Official URL: http://www.sciencedirect.com/science/article/pii/S...

Users with ORCIDS

Catalogue record

Date Deposited: 22 Jan 2018 16:39
Last Modified: 30 Sep 2020 11:17

Contributors

Author: Sophie Hodgetts
Author: Markus Hausmann
Author: Susanne Weis

University Divisions

Faculty of Health Sciences and Wellbeing
Faculty of Health Sciences and Wellbeing > School of Psychology

Subjects

Sciences > Biomedical Sciences
Psychology > Cognitive Behaviour
Psychology > Neuropsychology
Psychology > Psychology
Sciences

Actions (login required)

View Item (Repository Staff Only) View Item (Repository Staff Only)