Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.
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Urban-Wójciuk, Zuzanna, Graham, Amy, Barker, Karen, Kwok, Colin, Sbirkov, Yordan, Howell, Louise, Campbell, James, Woster, Patrick M, Poon, Evon, Petrie, Kevin and Chesler, Louis (2021) The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme. Cancer gene therapy. ISSN 1476-5500
Gil, Veronica S, Bhagat, Govind, Howell, Louise, Zhang, Jiyuan, Kim, Chae H, Stengel, Sven, Vega, Francisco, Zelent, Arthur and Petrie, Kevin (2016) Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice. Disease models & mechanisms, 9 (12). pp. 1483-1495. ISSN 1754-8411
Bansal, Nidhi, Petrie, Kevin, Christova, Rossitza, Chung, Chi-Yeh, Leibovitch, Boris A, Howell, Louise, Gil, Veronica, Sbirkov, Yordan, Lee, EunJee, Wexler, Joanna, Ariztia, Edgardo V, Sharma, Rajal, Zhu, Jun, Bernstein, Emily, Zhou, Ming-Ming, Zelent, Arthur, Farias, Eduardo and Waxman, Samuel (2015) Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer. Oncotarget, 6 (33). pp. 34087-105. ISSN 1949-2553
Cubedo, Elena, Gil, Veronica, Kim, Chae Hwa, Campuzano-Zuluaga, German, Agarwal, Nitin Kumar, Howell, Louise, Petrie, Kevin R, Vega, Francisco and Zelent, Arthur (2015) Abstract LB-160: HDAC9 expression is deregulated in malignant B-cell lymphomas in particular in diffuse large B-cell lymphoma and mantle cell lymphoma. Cancer Research, 75 (15_Sup). LB-160. ISSN 0008-5472
Kwon, Yeon-Jin, Petrie, Kevin, Leibovitch, Boris A, Zeng, Lei, Mezei, Mihaly, Howell, Louise, Gil, Veronica, Christova, Rossitza, Bansal, Nidhi, Yang, Shuai, Sharma, Rajal, Ariztia, Edgardo V, Frankum, Jessica, Brough, Rachel, Sbirkov, Yordan, Ashworth, Alan, Lord, Christopher J, Zelent, Arthur, Farias, Eduardo, Zhou, Ming-Ming and Waxman, Samuel (2015) Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer. Molecular cancer therapeutics, 14 (8). pp. 1824-36. ISSN 1538-8514
Ahmad, Zai, Jasnos, Lukasz, Gil, Veronica, Howell, Louise, Hallsworth, Albert, Petrie, Kevin, Sawado, Tomoyuki and Chesler, Louis (2015) Molecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastoma. PloS one, 10 (3). e0119834. ISSN 1932-6203
Hill, Rebecca M, Kuijper, Sanne, Lindsey, Janet C, Petrie, Kevin, Schwalbe, Ed C, Barker, Karen, Boult, Jessica K R, Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L, Poon, Evon, Robinson, Simon P, Ruddle, Ruth, Raynaud, Florence I, Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W, Wharton, Stephen B, Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S, Pizer, Barry, Bailey, Simon, Swartling, Fredrik J, Weiss, William A, Chesler, Louis and Clifford, Steven C (2015) Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease. Cancer cell, 27 (1). pp. 72-84. ISSN 1878-3686
Cubedo, Elena, Gil, Veronica Sylvina, Kim, Chae Hwa, Campuzano-Zuluaga, German, Agarwal, Nitin Kumar, Howell, Louise, Petrie, Kevin R., Vega, Francisco and Zelent, Arthur (2014) Abstract 5374: HDAC9 Expression Is Deregulated in Malignant B-Cell Lymphomas in Particular in Diffuse Large B Cell Lymphoma and Mantle Cell Lymphoma. Blood, 124 (21). p. 5374. ISSN 0006-4971
Christova, Rossitza, Petrie, Kevin, Bansal, Nidhi, Leibovitch, Boris, Howell, Louise, Gil, Veronica, Zhou, Ming-Ming, Ariztia, Edgardo, Farias, Eduardo, Zelent, Arthur and Waxman, Samuel (2014) Abstract 411: Targeted PF1, JARID1B inhibition induces epigenetic reprogramming in triple negative breast cancer. Cancer Research, 74 (19_Sup). p. 411. ISSN 0008-5472
Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet, Schwalbe, Ed C., Barker, Karen, Boult, Jessica, Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra, Poon, Evon, Robinson, Simon, Ruddle, Ruth, Raynaud, Florence, Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah, Crosier, Stephen, Wharton, Stephen, Jacques, Tom, Robson, Keith, Michalski, Antony, Hargrave, Darren, Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Petrie, Kevin, Weiss, William A., Chesler, Louis and Clifford, Steve (2014) Abstract LB-201: MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically. Cancer Research, 74 (19_Sup). LB-201. ISSN 0008-5472
Hill, Rebecca M, Kuijper, Sanne, Lindsey, Janet C, Petrie, Kevin, Schwalbe, Ed C, Barker, Karen, Boult, Jessica K R, Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L, Poon, Evon, Robinson, Simon P, Ruddle, Ruth, Raynaud, Florence I, Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Wharton, Stephen B, Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S, Pizer, Barry, Bailey, Simon, Swartling, Fredrik J, Weiss, William A, Chesler, Louis and Clifford, Steven C (2014) Abstract MB-013: MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically. Neuro-Oncology, 16 (Sup 1). i74-i74. ISSN 1522-8517
Gil, Veronica Sylvina, Stengel, Sven, Bhagat, Govind, Howell, Louise, Catovsky, Daniel, Pasqualucci, Laura, Petrie, Kevin and Zelent, Arthur (2012) Abstract 3505: Deregulated Expression of HDAC9 in B-Cells Leads to Lymphoproliferative Disorders As Well As Germinal Center and Post-Germinal Center Derived Lymphomas. Blood, 120 (21). p. 3505. ISSN 0006-4971
Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin and Zelent, Arthur (2012) Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nature medicine, 18 (4). pp. 605-11. ISSN 1546-170X
Schenk, Tino, Göllner, Stefanie, Chen, Weihsu Claire, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Burnett, Alan K, Mills, Ken I., Marton, Laurence, Casero, Robert, Woster, Patrick, Dugas, Martin, Wang, Jean C.Y., Dick, John E., Müller-Tidow, Carsten, Petrie, Kevin and Zelent, Arthur (2011) Abstract 224: Histone H3 Methylation Mediates All-Trans-Retinoic Acid Responsiveness in Acute Myeloid Leukemia. Blood, 118 (21). p. 224. ISSN 0006-4971
Petrie, Kevin R., Schenk, Tino, Chornet, Manuel Boix, Howell, Louise, Dick, John E, Marquez, Victor E, Marton, Laurence J, Woster, Patrick M, Casero, Robert A and Zelent, Arthur (2009) Abstract 1046: Modulation of Histone H3K4 and H3K27 Methylation Levels Via Pharmacological Inhibition of LSD1 and Degradation of the EZH2-Containing Polycomb Repressive Complex 2 Stimulates ATRA-Mediated Differentiation of AML Cells. Blood, 114 (22). p. 1046. ISSN 0006-4971
Gil, Veronica S., Petrie, Kevin, Chornet, Manuel Boix, Howell, Louise, Sebire, Neil J. and Zelent, Arthur (2006) Abstract 1433: Mice Overexpressing Histone Deacetylase 9 Display Abnormal B Cell Development and Proliferation. Blood, 108 (11). p. 1433. ISSN 0006-4971
Zelent, Arthur, Esteller, Manel, Piris, Miguel Angel, Waxman, Samuel, Matutes, Estella, Howell, Louise and Petrie, Kevin (2004) Abstract 1120: The Histone Deacetylase 9 Gene Is Regulated by Multiple Promoters and Expresses Lymphoid-Specific Isoforms. Blood, 104 (11). p. 1120. ISSN 0006-4971
Petrie, Kevin, Guidez, Fabien, Howell, Louise, Healy, Lyn, Waxman, Samuel, Greaves, Mel and Zelent, Arthur (2003) The histone deacetylase 9 gene encodes multiple protein isoforms. The Journal of biological chemistry, 278 (18). pp. 16059-72. ISSN 0021-9258