Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.
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Sbirkov, Yordan, Vergov, Bozhidar, Dzharov, Vasil, Schenk, Tino, Petrie, Kevin and Sarafian, Victoria (2023) Targeting Glutaminolysis Shows Efficacy in Both Prednisolone-Sensitive and in Metabolically Rewired Prednisolone-Resistant B-Cell Childhood Acute Lymphoblastic Leukaemia Cells. International Journal of Molecular Sciences, 24 (4). pp. 1-15. ISSN 1422-0067
Stengel, Sven, Petrie, Kevin, Sbirkov, Yordan, Stanko, Clara, Zadegan, Faezeh Ghazvini, Gil, Veronica, Skopek, Rafał, Kamiński, Pawel, Szymański, Łukasz, Brioli, Annamaria, Zelent, Arthur and Schenk, Tino (2022) Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all-trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia. British Journal of Haematology, 198 (2). pp. 338-348. ISSN 1365-2141
Sbirkov, Yordan, Ivanova, Tsvetomira, Burnusuzov, Hasan, Gercheva, Kalina, Petrie, Kevin, Schenk, Tino and Sarafian, Victoria (2021) The Protozoan Inhibitor Atovaquone Affects Mitochondrial Respiration and Shows In Vitro Efficacy Against Glucocorticoid-Resistant Cells in Childhood B-Cell Acute Lymphoblastic Leukaemia. Frontiers in oncology, 11. p. 632181. ISSN 2234-943X
Kahl, Melanie, Brioli, Annamaria, Bens, Martin, Perner, Florian, Kresinsky, Anne, Schnetzke, Ulf, Hinze, Anna, Sbirkov, Yordan, Stengel, Sven, Simonetti, Giorgia, Martinelli, Giovanni, Petrie, Kevin, Zelent, Arthur, Böhmer, Frank-Dietmar, Groth, Marco, Ernst, Thomas, Heidel, Florian H, Scholl, Sebastian, Hochhaus, Andreas and Schenk, Tino (2019) The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML. Leukemia, 33 (11). pp. 2628-2639. ISSN 1476-5551
Schenk, Tino, Stengel, Sven, Kahl, Melanie, Rodriguez, Ana, Perez, Aymee, Swords, Ronan T, Petrie, Kevin and Zelent, Arthur (2016) Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie. Abstract P500: Suppression of c-Myc by PAM pathway inhibition and ATRA treatment for therapeutic gain in acute myeloid leukemia. Oncology Research and Treatment, 39 (3). p. 145. ISSN 2296-5270
Swords, Ronan T., Schenk, Tino, Stengel, Sven, Gil, Veronica Sylvina, Petrie, Kevin R., Perez, Aymee, Ana, Rodriguez, Watts, Justin M., Vargas, Fernando, Elias, Roy and Zelent, Arthur (2015) Abstract 1363: Inhibition of the PI3K/AKT/mTOR Pathway Leads to Down-Regulation of c-Myc and Overcomes Resistance to ATRA in Acute Myeloid Leukemia. Blood, 126 (23). p. 1363. ISSN 0006-4971
Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin and Zelent, Arthur (2012) Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nature medicine, 18 (4). pp. 605-11. ISSN 1546-170X
Schenk, Tino, Göllner, Stefanie, Chen, Weihsu Claire, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Burnett, Alan K, Mills, Ken I., Marton, Laurence, Casero, Robert, Woster, Patrick, Dugas, Martin, Wang, Jean C.Y., Dick, John E., Müller-Tidow, Carsten, Petrie, Kevin and Zelent, Arthur (2011) Abstract 224: Histone H3 Methylation Mediates All-Trans-Retinoic Acid Responsiveness in Acute Myeloid Leukemia. Blood, 118 (21). p. 224. ISSN 0006-4971
Farias, Eduardo F, Petrie, Kevin, Leibovitch, Boris, Murtagh, Janice, Chornet, Manuel Boix, Schenk, Tino, Zelent, Arthur and Waxman, Samuel (2010) Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 107 (26). pp. 11811-6. ISSN 1091-6490
Petrie, Kevin R., Schenk, Tino, Chornet, Manuel Boix, Howell, Louise, Dick, John E, Marquez, Victor E, Marton, Laurence J, Woster, Patrick M, Casero, Robert A and Zelent, Arthur (2009) Abstract 1046: Modulation of Histone H3K4 and H3K27 Methylation Levels Via Pharmacological Inhibition of LSD1 and Degradation of the EZH2-Containing Polycomb Repressive Complex 2 Stimulates ATRA-Mediated Differentiation of AML Cells. Blood, 114 (22). p. 1046. ISSN 0006-4971