Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.
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Abdel Rahim, S., Carter, Paul and Elkordy, Amal (2015) Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug. Drug Design, Development and Therapy, 9. pp. 1843-1857. ISSN 1177-8881
Abdel Rahim, S. and Elkordy, Amal (2015) Formulation and evaluation of different floating tablets containing metronidazole to target stomach. Current Drug Delivery Journal, 12 (4). ISSN 1567-2018
Abuhamdah, S, Abuhamdah, R, Howes, M J, Al-Khali, S, Ennaceur, Abdelkader and Chazot, P (2015) Pharmacological profile of an essential oil derived from leaves of lemon verbena (Aloysia citriodora Palau): cholinergic, anti-oxidant and iron chelation properties. Journal of Pharmacy and Pharmacology. ISSN 2042-7158
Abuhamdah, S, Abuhamdah, Rushdie, Howes, Melanie-Jayne R., Al-Olimat, Suleiman, Ennaceur, Abdelkader and Chazot, Paul (2015) Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau. Journal of Pharmacy and Pharmacology, 67 (9). pp. 1306-1315. ISSN 2042-7158
Ahmed, Shafiq, Carruthers, R, Gilmour, L, Yildirim, S, Watts, C and Chalmers, A (2015) Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells. Cancer Research, 75 (20). pp. 4416-4428. ISSN 0008-5472
Armstrong, Jane, Hill, DS, McKee, CS, Hernandez-Tiedra, S, Lorente, M, Lopez-Valero, I, Eleni Anagnostou, M, Babatunde, F, Corazzari, M, Redfern, CP, Velasco, G and Lovat, PE (2015) Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death. Journal Of Investigative Dermatology, 135 (6). pp. 1629-1637. ISSN 0022-202X
Buyuk, Fatih, Sahin, Mitat, Cooper, Callum, Celebi, Ozgur, Saglam, Aliye Gulmez, Ballie, Les, Celik, Elif, Akca, Dogan and Otlu, Salih (2015) The effect of prolonged storage on the virulence of isolates of Bacillus anthracis obtained from environmental and animal sources in the Kars Region of Turkey. FEMS Microbiology Letters, 13 (1). ISSN 0378-1097
Chan, Ka Kui, Matchett, Kyle B., McEnhill, Paul M., Dakir, El Habib, McMullin, Mary Frances, El-Tanani, Yahia, Patterson, Laurence, Faheem, Ahmed, Rudland, Philip S., McCarron, Paul A. and El-Tanani, Mohamed (2015) Protein deregulation associated with breast cancer metastasis. Cytokine & Growth Factor Reviews, 26 (4). pp. 415-423. ISSN 1359 6101
Donovan, Gemma, Parkin, Lindsay and Wilkes, Scott (2015) Special unlicensed medicines: what we do and do not know about them. British Journal of General Practice, 65 (641). pp. 861-863. ISSN 0960-1643
Ennaceur, Abdelkader and Hussain, Muhammed Dilwar (2015) Effects of chronic fluoxetine treatment on anxious behaviour of BALB/c mice in a 3-dimensional maze. Stress. pp. 1-9. ISSN 1025-3890
Forgham, Helen, Johnson, Darren, Carter, Noel, Veuger, Stephany and Carr-Wilkinson, Jane (2015) Stem Cell Markers in Neuroblastoma—An Emerging Role for LGR5. Frontiers in Cell and Developmental Biology, 3 (77). ISSN 2296-634X
Haggag, Yusuf A. and Faheem, Ahmed (2015) Evaluation of nano spray drying as a method for drying and formulation of therapeutic peptides and proteins. Frontiers in Pharmacology, 6. ISSN 1663-9812
Haj-Ahmad, Rita, Chen, Y. T. and Elkordy, Amal (2015) An overview for the effects of lactitol, gelucire 44/14 and copovidone on lysozyme biological activity. European Journal of Biomedical and Pharmaceutical Sciences (EJBPS), 2 (3). pp. 1328-1339. ISSN 2349-8870
Haj-Ahmad, Rita, Elkordy, Amal and Chaw, Cheng (2015) In vitro characterisation of Span 65 niosomal formulations containing proteins. Current Drug Delivery Journal, 12 (5). 628-639(12). ISSN 1875-5704
Heussner, A.H. and Bingle, Lewis (2015) Comparative ochratoxin toxicity: a review of the available data. Toxins, 7 (10). pp. 4253-4282. ISSN 2072-6651
Hill, David, Robinson, Neil D. P., Caley, Matthew P., Chen, Mei, O'Toole, Edel A., Armstrong, Jane, Przyborski, Stefan and Lovat, Penny E. (2015) A novel fully-humanised 3D skin equivalent to model early melanoma invasion. Molecular Cancer Therapeutics, 14 (9). pp. 2665-2675. ISSN 1535-7163
Ichim, G, Lopez, J, Ahmed, Shafiq, Muthalagu, N, Giampazolias, E, Delgado, E, Haller, Martina, Riley, Joel S, Mason, Susan, Athineos, Dimitris, Parsons, MJ, Kooij, BVD, Bouchier-Hayes, L, Chalmers, A, Rooswinkel, R, Oberst, A, Blyth, K, Rehm, M, Murphy, D and Tait, S (2015) Limited mitochondrial permeabilisation causes DNA-damage and genomic instability in the absence of cell death. Molecular Cell, 57 (5). pp. 860-872. ISSN 1097-2765
Kumpan, K., Nathubhai, Amit, Zhang, C., Wood, P.J., Lloyd, M.D., Thompson, A.S., Haikarainen, T., Lehtiö, L. and Threadgill, M.D. (2015) Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases. Bioorganic & Medicinal Chemistry, 23. pp. 3013-3032. ISSN 0968-0896
Loh, Z.C. and Elkordy, Amal (2015) Formulation and evaluation of different floating tablets containing metronidazole to target stomach. Current Drug Delivery Journal, 12 (4). pp. 425-443. ISSN 1567-2018
Madi, HA, Dinah, C, Rees, Jon and Steel, DH (2015) The Case Mix of Patients Presenting with Full-Thickness Macular Holes and Progression before Surgery: Implications for Optimum Management. Opthalmologica, 233 (3-4). pp. 216-221. ISSN 0030-3755
Malcomson, Thomas, Yelekci, Kemal, Borrello, Maria Teresa and Arasu, Ganesan (2015) cis-cyclopropylamines as mechanism-based inhibitors of monoamine oxidases. The FEBS Journal, 282 (16). pp. 3190-3198. ISSN 1742-464X (In Press)
Nakonieczna, A, Cooper, Callum and Gryko, R (2015) Bacteriophages and bacteriophage‐derived endolysins as potential therapeutics to combat Gram‐positive spore forming bacteria. Journal of Applied Microbiology, 119 (3). pp. 620-631. ISSN 1364-5072
Paine, H.A., Nathubhai, Amit, Woon, E.C.Y., Sunderland, P.T., Wood, P.J., Mahon, M.F., Lloyd, M.D., Thompson, A.S., Haikarainen, T., Narwal, M., Lehtiö, L. and Threadgill, M.D. (2015) Exploration of the nicotinamide-binding site of the tankyrases,identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro. Bioorganic & Medicinal Chemistry, 23. pp. 5891-5908. ISSN 0968-0896
Rodriguez-Teja, M., Gronau, J. H., Minamidate, A., Darby, Steven, Gaughan, L., Robson, C., Mauri, F., Waxman, J. and Sturge, J. (2015) Survival Outcome and EMT Suppression Mediated by a Lectin Domain Interaction of Endo180 and CD147. Molecular Cancer Research, 13 (3). pp. 538-547. ISSN 1541-7786
Rodriguez-Teja, m, Gronau, JH, Breit, C, Zhang, YZ, Minamidate, A, Caley, MP, McCarthy, A, Cox, TR, Erler, JT, Gaughan, L, Darby, Steven, Robson, CN, Mauri, F, Waxman, J and Sturge, J (2015) AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival. Journal of Pathology, 235 (4). pp. 581-592. ISSN 1096-9896
Tardito, S, Oudin, A, Ahmed, Shafiq, Fack, F, Keunen, O, Zheng, L, Miletic, H, Sakariassen, P, Weinstock, A, Wagner, A, Lindsay, S, Hock, A, Barnett, S, Ruppin, E, Morkve, S, Lund-Johansen, M, Chalmers, A, Bjerkvig, R, Niclou, S and Gottlieb, E (2015) Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restriced glioblastoma. Nature Cell Biology, 17 (12). pp. 1556-1568. ISSN 1465-7392
Twum, E.A., Nathubhai, Amit, Wood, P.J., Lloyd, M.D., Thompson, A.S. and Threadgill, M.D. (2015) Initial development of a cytotoxic amino-seco-CBI warhead for delivery by prodrug systems. Bioorganic & Medicinal Chemistry, 23. pp. 3481-3489. ISSN 0968-0896
West, Sophie and Bhugra, Praveen (2015) Emerging drug targets for Aβ and tau in Alzheimer's disease: a systematic review. British Journal of Clinical Pharmacology, 80 (2). pp. 221-234. ISSN 0306 5251
Wong, Rachel, Ashton, Mark and Dodou, Kalliopi (2015) Effect of Crosslinking Agent Concentration on the Properties of Unmedicated Hydrogels. Pharmaceutics, 7 (3). pp. 305-319. ISSN 1999-4923
Hann, Victoria and Ashton, Mark (2015) HIV Integrase - Biology and Inhibitor Design. In: Frontiers in Clinical Drug Research - HIV. Bentham Science Publishers, pp. 185-286. ISBN 978-1-60805-897-6
Pearson, Pauline, Scott, Lesley, Hardisty, Jessica and Green, Alan (2015) Educational Interventions. In: Safety in Medication Use. Routledge, pp. 171-186. ISBN 9781482227000
Abu Abed, O. S., Chaw, Cheng, Carlile, Mark and Elkordy, Amal (2015) Evaluating the effect of pH, buffer conditions, and excipients on conformational stability of trypsin. In: 50th Anniversary Conference of the RSC Thermal Methods Group, 30 Mar - 1 Apr 2015, Churchill College, Cambridge, UK. (Unpublished)
Abu Abed, O. S., Chaw, Cheng, Carlile, Mark, Williams, Lee and Elkordy, Amal (2015) Effects of copolymer type and excipient on the size and encapsulation efficiency of lysozyme containing nanocapsules. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)
Anderson, Rosaleen (2015) Suicide substrates for pathogen identification in clinical diagnostics. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Submitted)
Carr-Wilkinson, Jane (2015) Differentiation of human embryonic stem cells to sympathetic neurons: A potential model for understanding neuroblastoma pathogenesis. In: American Association for Cancer Research: Developmental Biology and Cancer, 30 Nov-3 Dec 2015, Boston, USA. (Submitted)
Carr-Wilkinson, Jane (2015) High LGR5 expression is associated with an aggressive phenotype in neuroblastoma cells. In: American Association for Cancer Research: Developmental Biology and Cancer, 30 Nov-3 Dec 2015, Boston, USA. (Submitted)
Dewan, Nayema, Khalil, Bishoy, Wilkinson, Simon and Dodou, Kalliopi (2015) Studies on a Semisolid Emulsion of Doxycycline for Transdermal Drug Delivery. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 Jul 2015, Edinburgh, Scotland. (Submitted)
Donovan, Gemma (2015) Exploring Multidisciplinary Use of unLicenSed medicines In primary and secONdary care. In: Primary Care Research Forum, 24th September 2015, Marriott Hotel, Metro Centre, Gateshead.
Donovan, Gemma (2015) Research Fundamentals: getting in to research and developing your career. In: UKCPA Autumn Symposium 2015, 13 - 14 Nov 2015, The Mariott Hotel, Leicester. (Unpublished)
Donovan, Gemma and Armstrong, Catherine (2015) Pharmacy Placements in General Practice. In: Royal Pharmaceutical Society Annual Conference 2015, 13 - 14 Sep 2015, International Convention Centre, Birmingham.
Donovan, Gemma, Parkin, Lindsay, Brierley-Jones, Lyn and Wilkes, Scott (2015) Unlicensed medicines use in the UK: A systematic review and quality assessment of published guidelines. In: UKCPA Autumn Symposium 2015, 13 - 14 Nov 2015, The Marriott Hotel, Leicester.
Elkordy, Amal (2015) Formulation of liposomal drug delivery systems. In: Enhancing Nanoparticle Formulation & Scale Up: Microfluidics Users-group meeting, 3 Nov 2015, Aston University, Birmingham, UK. (Unpublished)
Elkordy, Amal (2015) A case study to reflect academic views on how student engagement shapes the student future. In: Three Rivers Learning and Teaching Conference: Student Engagement, 27 Mar 2015, St Peter's Campus, University of Sunderland, UK. (Unpublished)
Hadjipour, Azhidhack, Palmer, Rena-Jean, Zarara, Mohamed and Elkordy, Amal (2015) Floating Drug Delivery Systems with Xanthan Gum, Eudragit-RS PO or Lubritose SD: Nizatidine and Piracetam as Model Drugs. In: 1st International Electronic Conference on Medicinal Chemistry, 2-27 Nov 2015, Internet-based. (Submitted)
Hinshaw, Kim, Nayar, R, Emmerson, C, Johnson, J, Wilkes, Scott, Hewitt, L, Herdman, K, Purvis, A, Rees, J, Walker, R, Weaver, J, Esen, U, Mettayil, J, Marriott, P, Smart, J, Allan, E and Forbister, R (2015) Evaluation of telehealth monitoring in pregnancy using a multimatrix, multipartner model - a Northeast and North Cumbria AHSN innovation funded project. In: British Maternal & Fetal Medicine Society 2015, 23-24 Apr 2015, Queen Elizabeth II Conference Centre, London. (Submitted)
Javaheri, H., Elkordy, Amal and Carter, Paul (2015) Dissolution study of liquisolid compacts containing metformin: Overcoming the issue of poor powder flowability and compactibility using wet granulation technique. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)
Karamperopoulos, Polydoros, Fletcher, Ian, Wheatley, Alan and Dodou, Kalliopi (2015) Preliminary Studies on the Design of a Temperature Regulated Patch. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 25-29 Jul 2015, Edinburgh, Scotland. (Submitted)
McMahon, Fiona, Dawson, Peter, Anderson, Rosaleen, Sattelle, Ben, Warrender, Robert and Gray, Mark (2015) Development of Functional Computational Workflow Methods for Quality Automated Molecular Modelling-based Drug Design. In: MGMS Young Modellers Forum 2015, 27 Nov 2015, Greenwich, London. (Submitted)
Morgan, Y. R., Al Meanazel, O., Ali, L. and Elkordy, Amal (2015) Characterization of DNA complexes with cyclodextrin and polyethyleneglycol bisphenol A as potential formulations for gene therapy. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)
Mustafa, M. O., Hatemi, E., Hatemi, A. and Elkordy, Amal (2015) Effect of gluconolactone and polyethyleneglycol bisphenol A epichlorohydrin copolymer with lysozyme solution. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)
Palmer, R. and Elkordy, Amal (2015) Feasibility of using Lubritose SD to enhance properties of Piracetam floating tablets. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)
Rezwana, S. A. and Elkordy, Amal (2015) Designing of some floating tablets. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)
Salem, A., Bhatia, P., Vasseur, A. and Elkordy, Amal (2015) Effect of polyethyleneglycol bisphenol A epichlorohydrin copolymer and gluconolactone on trypsin biological activity. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 July 2015, Edinburgh, Scotland. (Unpublished)
Suliman, A.S., Anderson, Rosaleen and Elkordy, Amal (2015) Liquisolid technique in combination with wet granulation process for improving norfloxacin dissolution. In: Formulation and Drug Delivery Conference 2015, 18-19 May 2015, Kensington Close Hotel, London, UK. (Unpublished)
Surianarayanan, U. D. and Elkordy, Amal (2015) Formulation and characterization of fast disintegrating tablets with Furosemide. In: 6th APS International PharmSci 2015, Innovation in Pharmaceutical Sciences, 7 - 9 Sept 2015, East Midlands Conference Centre, Nottingham, UK. (Unpublished)
Wong, Rachel, Ashton, Mark, Wolff, Hans and Dodou, Kalliopi (2015) Effect of Photoinitiator Concentration on the Properties of Unmedicated Hydrogels. In: 42nd Annual Meeting & Exposition of the Controlled Release Society, 26-29 Jul 2015, Edinburgh, Scotland. (Submitted)