Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.
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Chen, Rui, Lukianova, Elena, van der Loeff, Ina Schim, Spegarova, Jarmila Stremenova, Willet, Joseph D.P., James, Kieran D., Ryder, Edward J., Griffin, Helen, IJspeert, Hanna, Gajbhiye, Akshada, Lamoliatte, Frederic, Marin-Rubio, Jose L., Woodbine, Lisa, Lemos, Henrique, Swan, David J., Pintar, Valeria, Sayes, Kamal, Ruiz-Morales, Elias R., Eastham, Simon, Dixon, David, Prete, Martin, Prigmore, Elena, Jeggo, Penny, Boyes, Joan, Mellor, Andrew, Huang, Lei, van der Burg, Mirjam, Engelhardt, Karin R., Stray-Pedersen, Asbjørg, Erichsen, Hans Christian, Gennery, Andrew R., Trost, Matthias, Adams, David J., Anderson, Graham, Lorenc, Anna, Trynka, Gosia and Hambleton, Sophie (2024) NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and Omenn syndrome. Science Immunology, 9 (95). ISSN 2470-9468
Baker, Kenneth, McDonald, David, Hulme, Gillian, Hussain, Rafiqul, Coxhead, Jonathan, Swan, David, Schulz, Axel, Mei, Henrik, MacDonald, Lucy, Pratt, Arthur, Filby, Andrew, Anderson, Amy and Isaacs, John (2024) Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature Communications. ISSN ISSN 2041-1723
Ewen, Tom, Husain, Akhtar, Stefanos, Niki, Barrett, Paul, Jones, Claire, Ness, Tom, Long, Anna, Horswell, Stuart, Bosomworth, Helen, Lowenstein, Joe, Richardson, Grant, Swan, David, McConnell, Ashleigh, Rose, Aidan, Andrew, Tom, Reynolds, Nick, Malvehy, Josep, Carrera, Christina, Also, Llucia, Mailer, Sonia, Helm, Thomas, Ding, Liang, Bogner, Paul, Podlipnik, Sebastian, Puig, Susana, McArthur, Grant, Paragh, Gyorgy, Labus, Marie, Sloan, Philip, Armstrong, Jane and Lovat, Penny (2023) Validation of Epidermal AMBRA1 and Loricrin (AMBLor) as a prognostic biomarker for non-ulcerated AJCC stage I/II cutaneous melanoma. British Journal of Dermatology. ISSN 0007-0963
Swan, David, Aschenbrenner, Dominik, Lamb, Christopher A, Chakraborty, Krishnendu, Clark, Jonathan, Pandey, Sumeet, Engelhardt, Karin R, Chen, Rui, Cavounidis, Athena, Ding, Yuchun, Krasnogor, Natalio, Carey, Christopher D, Acres, Meghan, Needham, Stephanie, Cant, Andrew J, Arkwright, Peter D, Chandra, Anita, Okkenhaug, Klaus, Uhlig, Holm H and Hambleton, Sophie (2019) Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of -encoded phosphoinositide 3-kinase δ. Haematologica, 104 (10). e483-e486. ISSN 0390-6078
Anzilotti, Consuelo, Swan, David, Boisson, Bertrand, Deobagkar-Lele, Mukta, Oliveira, Catarina, Chabosseau, Pauline, Engelhardt, Karin R, Xu, Xijin, Chen, Rui, Alvarez, Luis, Berlinguer-Palmini, Rolando, Bull, Katherine R, Cawthorne, Eleanor, Cribbs, Adam P, Crockford, Tanya L, Dang, Tarana Singh, Fearn, Amy, Fenech, Emma J, de Jong, Sarah J, Lagerholm, B Christoffer, Ma, Cindy S, Sims, David, van den Berg, Bert, Xu, Yaobo, Cant, Andrew J, Kleiner, Gary, Leahy, T Ronan, de la Morena, M Teresa, Puck, Jennifer M, Shapiro, Ralph S, van der Burg, Mirjam, Chapman, J Ross, Christianson, John C, Davies, Benjamin, McGrath, John A, Przyborski, Stefan, Santibanez Koref, Mauro, Tangye, Stuart G, Werner, Andreas, Rutter, Guy A, Padilla-Parra, Sergi, Casanova, Jean-Laurent, Cornall, Richard J, Conley, Mary Ellen and Hambleton, Sophie (2019) An essential role for the Zn transporter ZIP7 in B cell development. Nature immunology, 20 (3). pp. 350-361. ISSN 1529-2916
Acres, Meghan J, Gothe, Florian, Grainger, Angela, Skelton, Andrew J, Swan, David, Willet, Joseph D P, Leech, Suzy, Galcheva, Sonya, Iotova, Violeta, Hambleton, Sophie and Engelhardt, Karin R (2018) Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain. Journal of allergy and clinical immunology, 143 (1). 413-416.e4. ISSN 0091-6749
Duncan, Christopher J A, Dinnigan, Emma, Theobald, Rachel, Grainger, Angela, Skelton, Andrew J, Hussain, Rafiqul, Willet, Joseph D P, Swan, David, Coxhead, Jonathan, Thomas, Matthew F, Thomas, Julian, Zamvar, Veena, Slatter, Mary A, Cant, Andrew J, Engelhardt, Karin R and Hambleton, Sophie (2018) Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in (A20). Annals of the rheumatic diseases, 77 (5). pp. 783-786. ISSN 1468-2060
Taylor, K, Swan, David, Affleck, A, Flohr, C and Reynolds, N J (2017) Treatment of moderate-to-severe atopic eczema in adults within the U.K.: results of a national survey of dermatologists. The British journal of dermatology, 176 (6). pp. 1617-1623. ISSN 0007-0963
Engelhardt, Karin R, Xu, Yaobo, Grainger, Angela, Germani Batacchi, Mila G C, Swan, David, Willet, Joseph D P, Abd Hamid, Intan J, Agyeman, Philipp, Barge, Dawn, Bibi, Shahnaz, Jenkins, Lucy, Flood, Terence J, Abinun, Mario, Slatter, Mary A, Gennery, Andrew R, Cant, Andrew J, Santibanez Koref, Mauro, Gilmour, Kimberly and Hambleton, Sophie (2017) Identification of Heterozygous Single- and Multi-exon Deletions in IL7R by Whole Exome Sequencing. Journal of clinical immunology, 37 (1). pp. 42-50. ISSN 1573-2592
Anderson, A E, Swan, David, Wong, O Y, Buck, M, Eltherington, O, Harry, R A, Patterson, A M, Pratt, A G, Reynolds, G, Doran, J-P, Kirby, J A, Isaacs, J D and Hilkens, C M U (2016) Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4 T cells partly via transforming growth factor-β1. Clinical and experimental immunology, 187 (1). pp. 113-123. ISSN 0009-9104
Milner, Joshua D., Vogel, Tiphanie P., Forbes, Lisa, Ma, Chi A., Stray-Pedersen, Asbjørg, Niemela, Julie E., Lyons, Jonathan J., Engelhardt, Karin R., Zhang, Yu, Topcagic, Nermina, Roberson, Elisha D. O., Matthews, Helen, Verbsky, James W., Dasu, Trivikram, Vargas-Hernandez, Alexander, Varghese, Nidhy, McClain, Kenneth L., Karam, Lina B., Nahmod, Karen, Makedonas, George, Mace, Emily M., Sorte, Hanne S., Perminow, Gøri, Rao, V. Koneti, O’Connell, Michael P., Price, Susan, Su, Helen C., Butrick, Morgan, McElwee, Joshua, Hughes, Jason D., Willet, Joseph, Swan, David, Xu, Yaobo, Santibanez-Koref, Mauro, Slowik, Voytek, Dinwiddie, Darrell L., Ciaccio, Christina E., Saunders, Carol J., Septer, Seth, Kingsmore, Stephen F., White, Andrew J., Cant, Andrew J., Hambleton, Sophie and Cooper, Megan A. (2015) Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. Blood, 125 (4). pp. 591-599. ISSN 0006-4971
Swan, David, Kirby, John A and Ali, Simi (2012) Post-transplant immunosuppression: regulation of the efflux of allospecific effector T cells from lymphoid tissues. PloS one, 7 (9). e45548. ISSN 1932-6203
Swan, David, Kirby, John A and Ali, Simi (2010) Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation. Journal of cellular and molecular medicine, 14 (9). pp. 2211-22. ISSN 1582-4934
Anderson, Amy E, Swan, David, Sayers, Bethan L, Harry, Rachel A, Patterson, Angela M, von Delwig, Alexei, Robinson, John H, Isaacs, John D and Hilkens, Catharien M U (2008) LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells. Journal of leukocyte biology, 85 (2). pp. 243-50. ISSN 0741-5400
Anderson, Amy E, Sayers, Bethan L, Haniffa, Muzlifah A, Swan, David, Diboll, Julie, Wang, Xiao-Nong, Isaacs, John D and Hilkens, Catharien M U (2008) Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells. Journal of leukocyte biology, 84 (1). pp. 124-133. ISSN 0741-5400