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Sunderland Repository records the research produced by the University of Sunderland including practice-based research and theses.

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Number of items: 32.

Article

Stengel, Sven, Petrie, Kevin, Sbirkov, Yordan, Stanko, Clara, Zadegan, Faezeh Ghazvini, Gil, Veronica, Skopek, Rafał, Kamiński, Pawel, Szymański, Łukasz, Brioli, Annamaria, Zelent, Arthur and Schenk, Tino (2022) Suppression of MYC by PI3K/AKT/mTOR pathway inhibition in combination with all-trans retinoic acid treatment for therapeutic gain in acute myeloid leukaemia. British Journal of Haematology, 198 (2). pp. 338-348. ISSN 1365-2141

Kahl, Melanie, Brioli, Annamaria, Bens, Martin, Perner, Florian, Kresinsky, Anne, Schnetzke, Ulf, Hinze, Anna, Sbirkov, Yordan, Stengel, Sven, Simonetti, Giorgia, Martinelli, Giovanni, Petrie, Kevin, Zelent, Arthur, Böhmer, Frank-Dietmar, Groth, Marco, Ernst, Thomas, Heidel, Florian H, Scholl, Sebastian, Hochhaus, Andreas and Schenk, Tino (2019) The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML. Leukemia, 33 (11). pp. 2628-2639. ISSN 1476-5551

Watts, Justin M, Perez, Aymee, Pereira, Lutecia, Fan, Yao-Shan, Brown, Geoffrey, Vega, Francisco, Petrie, Kevin, Swords, Ronan T and Zelent, Arthur (2017) A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy. International journal of molecular sciences, 18 (7). ISSN 1422-0067

Sbirkov, Yordan, Kwok, Colin, Bhamra, Amandeep, Thompson, Andrew J, Gil, Veronica, Zelent, Arthur and Petrie, Kevin (2017) Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase. International journal of molecular sciences, 18 (7). ISSN 1422-0067

Gil, Veronica S, Bhagat, Govind, Howell, Louise, Zhang, Jiyuan, Kim, Chae H, Stengel, Sven, Vega, Francisco, Zelent, Arthur and Petrie, Kevin (2016) Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice. Disease models & mechanisms, 9 (12). pp. 1483-1495. ISSN 1754-8411

Schenk, Tino, Stengel, Sven, Kahl, Melanie, Rodriguez, Ana, Perez, Aymee, Swords, Ronan T, Petrie, Kevin and Zelent, Arthur (2016) Jahrestagung der ­Deutschen, Österreichischen und ­Schweizerischen ­Gesellschaften für Hämatologie und ­Medizinische Onkologie. Abstract P500: Suppression of c-Myc by PAM pathway inhibition and ATRA treatment for therapeutic gain in acute myeloid leukemia. Oncology Research and Treatment, 39 (3). p. 145. ISSN 2296-5270

Kwon, Yeon-Jin, Leibovitch, Boris A., Bansal, Nidhi, Pereira, Lutecia, Ariztia, Edgardo V., Petrie, Kevin, Zelent, Arthur, Zhou, Ming-Ming, Farias, Eduardo F. and Waxman, Samuel (2016) Abstract 4115: Inhibition of triple negative breast cancer cell invasion by the targeted interference of Sin3A function affecting Wnt and TGFβ signaling. Cancer Research, 76 (14_Sup). p. 4115. ISSN 0008-5472

Swords, Ronan T., Schenk, Tino, Stengel, Sven, Gil, Veronica Sylvina, Petrie, Kevin R., Perez, Aymee, Ana, Rodriguez, Watts, Justin M., Vargas, Fernando, Elias, Roy and Zelent, Arthur (2015) Abstract 1363: Inhibition of the PI3K/AKT/mTOR Pathway Leads to Down-Regulation of c-Myc and Overcomes Resistance to ATRA in Acute Myeloid Leukemia. Blood, 126 (23). p. 1363. ISSN 0006-4971

Bansal, Nidhi, Petrie, Kevin, Christova, Rossitza, Chung, Chi-Yeh, Leibovitch, Boris A, Howell, Louise, Gil, Veronica, Sbirkov, Yordan, Lee, EunJee, Wexler, Joanna, Ariztia, Edgardo V, Sharma, Rajal, Zhu, Jun, Bernstein, Emily, Zhou, Ming-Ming, Zelent, Arthur, Farias, Eduardo and Waxman, Samuel (2015) Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer. Oncotarget, 6 (33). pp. 34087-105. ISSN 1949-2553

Cubedo, Elena, Gil, Veronica, Kim, Chae Hwa, Campuzano-Zuluaga, German, Agarwal, Nitin Kumar, Howell, Louise, Petrie, Kevin R, Vega, Francisco and Zelent, Arthur (2015) Abstract LB-160: HDAC9 expression is deregulated in malignant B-cell lymphomas in particular in diffuse large B-cell lymphoma and mantle cell lymphoma. Cancer Research, 75 (15_Sup). LB-160. ISSN 0008-5472

Kwon, Yeon-Jin, Petrie, Kevin, Leibovitch, Boris A, Zeng, Lei, Mezei, Mihaly, Howell, Louise, Gil, Veronica, Christova, Rossitza, Bansal, Nidhi, Yang, Shuai, Sharma, Rajal, Ariztia, Edgardo V, Frankum, Jessica, Brough, Rachel, Sbirkov, Yordan, Ashworth, Alan, Lord, Christopher J, Zelent, Arthur, Farias, Eduardo, Zhou, Ming-Ming and Waxman, Samuel (2015) Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer. Molecular cancer therapeutics, 14 (8). pp. 1824-36. ISSN 1538-8514

Cubedo, Elena, Gil, Veronica Sylvina, Kim, Chae Hwa, Campuzano-Zuluaga, German, Agarwal, Nitin Kumar, Howell, Louise, Petrie, Kevin R., Vega, Francisco and Zelent, Arthur (2014) Abstract 5374: HDAC9 Expression Is Deregulated in Malignant B-Cell Lymphomas in Particular in Diffuse Large B Cell Lymphoma and Mantle Cell Lymphoma. Blood, 124 (21). p. 5374. ISSN 0006-4971

Christova, Rossitza, Petrie, Kevin, Bansal, Nidhi, Leibovitch, Boris, Howell, Louise, Gil, Veronica, Zhou, Ming-Ming, Ariztia, Edgardo, Farias, Eduardo, Zelent, Arthur and Waxman, Samuel (2014) Abstract 411: Targeted PF1, JARID1B inhibition induces epigenetic reprogramming in triple negative breast cancer. Cancer Research, 74 (19_Sup). p. 411. ISSN 0008-5472

Petrie, Kevin, Field, Megan, Ahmad, Zai, Dezfouli, Mehrnoush, Barker, Karen, Jeznach, Magdalena, Glass, Laura, Hallsworth, Albert, Sbirkov, Yordan, Womersley, Howard, Zelent, Arthur, Jordan, Philip, Akoulitchev, Alexandre and Chesler, Louis (2013) Abstract LB-87: A novel epigenetic blood test to monitor minimal residual disease in high-risk neuroblastoma. Cancer Research, 73 (8_Supp). LB-87. ISSN 0008-5472

Gil, Veronica Sylvina, Stengel, Sven, Bhagat, Govind, Howell, Louise, Catovsky, Daniel, Pasqualucci, Laura, Petrie, Kevin and Zelent, Arthur (2012) Abstract 3505: Deregulated Expression of HDAC9 in B-Cells Leads to Lymphoproliferative Disorders As Well As Germinal Center and Post-Germinal Center Derived Lymphomas. Blood, 120 (21). p. 3505. ISSN 0006-4971

Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin and Zelent, Arthur (2012) Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nature medicine, 18 (4). pp. 605-11. ISSN 1546-170X

Schenk, Tino, Göllner, Stefanie, Chen, Weihsu Claire, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Burnett, Alan K, Mills, Ken I., Marton, Laurence, Casero, Robert, Woster, Patrick, Dugas, Martin, Wang, Jean C.Y., Dick, John E., Müller-Tidow, Carsten, Petrie, Kevin and Zelent, Arthur (2011) Abstract 224: Histone H3 Methylation Mediates All-Trans-Retinoic Acid Responsiveness in Acute Myeloid Leukemia. Blood, 118 (21). p. 224. ISSN 0006-4971

Farias, Eduardo F, Petrie, Kevin, Leibovitch, Boris, Murtagh, Janice, Chornet, Manuel Boix, Schenk, Tino, Zelent, Arthur and Waxman, Samuel (2010) Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 107 (26). pp. 11811-6. ISSN 1091-6490

Petrie, Kevin R., Schenk, Tino, Chornet, Manuel Boix, Howell, Louise, Dick, John E, Marquez, Victor E, Marton, Laurence J, Woster, Patrick M, Casero, Robert A and Zelent, Arthur (2009) Abstract 1046: Modulation of Histone H3K4 and H3K27 Methylation Levels Via Pharmacological Inhibition of LSD1 and Degradation of the EZH2-Containing Polycomb Repressive Complex 2 Stimulates ATRA-Mediated Differentiation of AML Cells. Blood, 114 (22). p. 1046. ISSN 0006-4971

Petrie, Kevin, Zelent, Arthur and Waxman, Samuel (2009) Differentiation therapy of acute myeloid leukemia: past, present and future. Current opinion in hematology, 16 (2). pp. 84-91. ISSN 1531-7048

Zelent, Arthur, Petrie, Kevin, Boix-Chornet, Manuel, Melnick, Ari M, Waxman, Samuel and Gore, Steven D (2008) Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics. Cancer research, 68 (13). pp. 4967-70. ISSN 1538-7445

Petrie, Kevin and Zelent, Arthur (2008) Marked for death. Nature cell biology, 10 (5). pp. 507-9. ISSN 1476-4679

Petrie, Kevin and Zelent, Arthur (2008) AML1/ETO, a promiscuous fusion oncoprotein. Blood, 109 (10). pp. 4109-4110. ISSN 0006-4971

Glasow, Annegret, Barrett, Angela, Petrie, Kevin, Gupta, Rajeev, Boix-Chornet, Manuel, Zhou, Da-Cheng, Grimwade, David, Gallagher, Robert, von Lindern, Marieke, Waxman, Samuel, Enver, Tariq, Hildebrandt, Guido and Zelent, Arthur (2008) DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia. Blood, 111 (4). pp. 2374-7. ISSN 0006-4971

Zelent, Arthur, So, Eric, Enver, Tariq, Wotherspoon, Andy, Matutes, Estela, Sebire, Neil, Smith, Adrian, Petrie, Kevin R., Yeung, Jenny, Howell, Louise M.C. and Gil, Veronica S. (2007) Abstract 376: Ectopic Expression of HDAC9 in Murine Lymphoid System Leads to Altered Lymphocyte Numbers and Proliferation as Well as Predisposition to Tumorigenesis. Blood, 110 (11). p. 376. ISSN 0006-4971

Gil, Veronica S., Petrie, Kevin, Chornet, Manuel Boix, Howell, Louise, Sebire, Neil J. and Zelent, Arthur (2006) Abstract 1433: Mice Overexpressing Histone Deacetylase 9 Display Abnormal B Cell Development and Proliferation. Blood, 108 (11). p. 1433. ISSN 0006-4971

Xu, Ke, Guidez, Fabien, Glasow, Annegret, Chung, Danna, Petrie, Kevin, Stegmaier, Kimberly, Wang, Kan-Kan, Zhang, Ji, Jing, Yongkui, Zelent, Arthur and Waxman, Samuel (2005) Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression. Cancer research, 65 (17). pp. 7856-65. ISSN 0008-5472

Zelent, Arthur, Petrie, Kevin, Chen, Zhu, Lotan, Reuben, Lübbert, Michael, Tallman, Martin S, Ohno, Ryuzo, Degos, Laurent and Waxman, Samuel (2005) Molecular target-based treatment of human cancer: summary of the 10th international conference on differentiation therapy. Cancer research, 65 (4). pp. 1117-23. ISSN 0008-5472

Zelent, Arthur, Esteller, Manel, Piris, Miguel Angel, Waxman, Samuel, Matutes, Estella, Howell, Louise and Petrie, Kevin (2004) Abstract 1120: The Histone Deacetylase 9 Gene Is Regulated by Multiple Promoters and Expresses Lymphoid-Specific Isoforms. Blood, 104 (11). p. 1120. ISSN 0006-4971

Petrie, Kevin, Guidez, Fabien, Howell, Louise, Healy, Lyn, Waxman, Samuel, Greaves, Mel and Zelent, Arthur (2003) The histone deacetylase 9 gene encodes multiple protein isoforms. The Journal of biological chemistry, 278 (18). pp. 16059-72. ISSN 0021-9258

Guidez, Fabien, Petrie, Kevin, Ford, Anthony M, Lu, Huafeng, Bennett, Caroline A, MacGregor, Angus, Hannemann, Jurgen, Ito, Yoshiaki, Ghysdael, Jaques, Greaves, Mel, Wiedemann, Leanne M. and Zelent, Arthur (2000) Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein. Blood, 96 (7). pp. 2557-61. ISSN 0006-4971

Patents

Institute of Cancer Research (GB) (2003) Histone deacetylase 9. WO-03029451-A2.

This list was generated on Tue Mar 5 04:31:20 2024 GMT.